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Research Snapshot: Vanderbilt team discovers potential explanation for treatment resistance in skin cancer

Research Snapshot: Vanderbilt team discovers potential explanation for treatment resistance in skin cancer
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CDK inhibitors may improve immune therapy effectiveness for recurrent breast cancer


Recurrent, metastatic breast cancer resists treatment and is usually fatal.
These tumors often have low numbers of immune cells in them, which renders immune therapies less effective for the disease.
This preclinical study suggests that drugs called CDK4 and CDK6 inhibitors may make immune-cell therapies an effective option for treating recurrent ER-positive metastatic breast cancer.
COLUMBUS, Ohio - A class of drugs that inhibits breast cancer progression when used with hormonal therapy might also boost the effectiveness of immune therapy in cases of recurrent, metastatic breast cancer, according to a new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James). ....

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