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Astronomy meets pathology to identify predictive biomarkers for cancer immunotherapy


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IMAGE: The AstroPath platform allows for the assessment of the level of expression of a given marker on individual cells, while maintaining information on their spatial location. Shown here is.
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Credit: Seyoun Park, Ph.D.
Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers at The Mark Foundation Center for Advanced Genomics and Imaging at Johns Hopkins University and the Bloomberg~Kimmel Institute for Cancer Immunotherapy developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system.
A new platform, called AstroPath, melds astronomic image analysis and mapping with pathology specimens to analyze microscopic images of tumors. ....

United States , Janis Taube , Charles Roberts , Evanj Lipson , Richard Wilton , Shlomit Jessel , Harriet Kluger , Evan Lipson , Inbalb Sander , Peter Nguyen , Jose Loyola , Qingfeng Zhu , Akoya Biosciences , Michele Cleary , Robert Anders , Suzannel Topalian , Elizabethm Jaffee , Ludmila Danilova , Elizabeth Engle , Margaret Eminizer , Daphne Wang , Sneha Berry , Aleksandra Ogurtsova , Angelo Demarzo , Haiying Xu , Roberta Anders ,