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genetic variants that influence the amount or function of human “helper proteins” that support or facilitate SARS-CoV-2. The gene variants reveal potential target structures for new drugs. The researchers have now published their results in Nature Communications. The team examined 179 proteins known to be involved in SARS-CoV-2 infection for their naturally occurring variants. They discovered 38 targets for existing drugs as well as evidence that certain proteins that interact with the virus influence the immune system. DOI: 10.1038/s41467-020-19996-z In all-cause excess mortality and ...

Share: BioCardia (NASDAQ: BCDA) shares are trading higher. The company said it anticipates data safety monitoring board verbal feedback by the end of Dec. 15 for its pivotal Phase 3 CardiAMP Heart Failure Trial. BioCardia is a clinical stage regenerative medicine company. It is developing therapeutics for cardiovascular diseases with large unmet medical needs. BioCardia shares were trading up 78.37% at $5.03. The stock has a 52-week range between $6.75 and $1.91. Pacific Biosciences (NASDAQ: PACB) shares are trading higher after the company announced three of the United Kingdom's leading core...

Leading UK Core Labs Expand Investment in PacBio Sequencing Systems to Power Life Science Research with HiFi Reads Edinburgh Genomics, Oxford Genomics Centre, and University of Liverpool Centre for Genomic Research have added new PacBio Sequel II & IIe Systems to their service laboratories Pacific Biosciences of California, Inc. Menlo Park, California, UNITED STATES MENLO PARK, Calif., Dec. 14, 2020 (GLOBE NEWSWIRE) -- Pacific Biosciences of California, Inc. (Nasdaq:PACB), a leading provider of high-quality sequencing of genomes, transcriptomes and epigenome...

 E-Mail IMAGE: Associate Professor Marcia Levitus from the School of Molecular Sciences at Arizona State University view more  Credit: Mary Zhu Many proteins are required to maintain the structure, and to preserve the genetic integrity, of DNA. Sliding clamps are proteins that increase the efficiency of DNA replication. Without these proteins, cells would not be able to carry out continuous DNA synthesis, and organisms, from bacteria to humans, would not survive. Sliding clamps are ring-shaped proteins that encircle DNA and bind to the DNA polymerase, the enzyme that performs the ac...