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DMT is the psychoactive agent found in Ayahuasca, a drink that has been prepared by Amazonian rainforest communities for thousands of years.
This gives new meaning to the phrase, 'take a chill pill.' Researchers at UC Santa Cruz have found that a non-hallucinogenic psychedelic similar to the psychoactive substance ibogaine drastically lowers the levels of stress in mice. A single dose of tabernanthalog (TBG) can lower anxiety and cognitive inflexibility in the rodents. It also has the ability to promote the regrowth of neuronal connections and restoring neural circuits that are negatively impacted from stress. 'It was very surprising that a single treatment with a low dose had such dramatic effects within a day,' said one of the...
Small Pharma on conducting world’s first clinical trials for psychedelic DMT and listing in Canada Small Pharma's (CVE:DMT) Peter Rands joins Proactive to introduce his company after launching on Toronto’s TSX Venture Exchange, raising C$58mln to develop medicines based on N,N-Dimethyltryptamine (DMT) to treat depression. The firm is committed to helping accelerate the development of effective therapeutic treatments for mental health disorders. The company is currently conducting the world’s first clinical trials exploring the potential for the psychedelic N, N-Dimethyltryptamine (DMT) ...
A newly-identified 'psychedelic-like drug' doesn't cause hallucinogenic side effects, scientists reveal. AAZ-A-154 is a 'previously unstudied' molecule that has the potential to act on beneficial pathways in the brain without causing hallucinations. It stimulates receptors for serotonin – a key hormone sent between nerve cells in our brain that stabilises our mood, well-being and happiness. In experiments on mice, AAZ-A-154 produced rapid and long-lasting antidepressant-like effects after a single dose, the US researchers found – and, if synthesised, could be an effective treatment fo...