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The researchers demonstrated that glucokinase activation was effective in lowering blood glucose in mice with high-fat diet-induced obesity, while it potentially raised the risk of increasing hepatic lipid accumulation that triggered the PERK-UPR pathway.
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Down-regulation of plasma fatty acid levels may reduce pancreatic β-cell dysfunction, thereby improving glucose homeostasis.
Investigating the effect and mechanism of lipotoxicity on HBV DNA replication.
The use of e-cigs increases the risk of acute respiratory syndrome.