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Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation


Researchers develop new method for charting SARS-CoV-2 spike protein glycosylation
Researchers have developed a novel, simple and affordable method for N-glycan fingerprinting based on enzymatic fluorescent glycan labeling and electrophoresis. This new method may help us understand important changes in glycosylation in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein – something which could inform future therapeutic research.
Advances in genomics, proteomics and mass spectrometry have enabled scientists to identify specific glycans on proteins and their association with diseases. However, these methods are expensive, require highly trained experts to perform and are not easily available.
Researchers Zhengliang L. Wu and James M. Ertelt released the N-glycans present on a glycoprotein and labeled them enzymatically using fluorophore-conjugated sialic acid and fucose, and separated them using gel electrophoresis. The fingerprint of the gly ....

Ramya Dwivedi , Coronavirus Disease Covid 19 , Sars Cov 2 , Spike Protein , Corona Virus , Gel Electrophoresis , Mass Spectrometry , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , ரம்யா டுவிவேடி , ஸ்பைக் ப்ரோடீந் , கொரோனா வைரஸ் , நிறை ஸ்பெக்ட்ரோமெட்ரி , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

REGISTER TODAY! Track and Identify Microplastic Contaminants with Hound


REGISTER TODAY! Track and Identify Microplastic Contaminants with Hound
Microplastics are everywhere you can’t see, from the mountains to the ocean to your food. Identifying the degree of contamination requires analytical tools that can see subvisible particles as well as identify them.
Microplastics. Image Credit: MikeDotta/Shutterstock.com
During this live webinar, Robin Sweeney, Product Manager at Unchained Labs, will discuss recently published work highlighting the advantages of using advanced automated microscopy powered by the combination of Raman spectroscopy and laser-induced breakdown spectroscopy (LIBS) as a means to collect and identify microplastics in various samples.
Key Learning Objectives
Overview of complete particle characterization from size, shape, and count to identification and source material ....

Robin Sweeney , Mikedotta Shutterstock , Image Credit , Product Manager , Unchained Labs , Raman Spectroscopy , ராபின் ஸ்வீனி , படம் கடன் , ப்ராடக்ட் மேலாளர் , அந்‌சேஂட் ஆய்வகங்கள் , ராமன் ஸ்பெக்ட்ரோஸ்கோபி ,