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Bipolar Breakthrough

  The main treatment for bipolar disorder, lithium, was approved a half-century ago but doesn't help all patients and has significant side effects. Little progress has been made in finding better therapies, in part because scientists don’t fully understand how the condition arises or exactly how lithium improves symptoms when it does work. ....

Harvard University , United States , Elizabeth Dauten , Steven Hyman , Duncan Palmer , Benjamin Neale , Broad Institute , National Institutes Of Health , Harvard Medical School , Stanley Family Foundation , Bipolar Exome Consortium , Stanley Center , Dalio Foundation , Psychiatric Research , Stem Cell , Regenerative Biology , Schizophrenia Exome Sequencing Meta Analysis , Massachusetts General , Population Genetics , National Institutes ,

Report sounds alarm on efficacy, safety, ethics of embryo selection with polygenic scores


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Special report conducted by multinational team of researchers from University of Southern California, Geisinger Health System, UCLA, National Bureau of Economic Research, New York University, Harvard University, Broad Institute of Harvard and MIT, Harvard Medical School, Massachusetts General Hospital, Brigham and Women s Hospital, University of Queensland
July 1, 2021 A special report published today in the
New England Journal of Medicine raises serious questions about the benefits, risks and ethics of a new service which the authors call embryo selection based on polygenic scores, or ESPS that allows in vitro fertilization patients to select embryos with the goal of choosing healthier and even smarter children. ....

Anderson School , United States , Harvard University , Nancy Wang , Michelle Meyer , Peterm Visscher , David Laibson , David Sampson , Heidil Rehm , Ashley Andyshak Hayes , Danielj Benjamin , Patrick Turley , David Cesarini , Jenesse Miller , Louise Wilkins Haug , Evelynn Hammonds , Aliciar Martin , Michellen Meyer , Steven Hyman , Benm Neale , National Health , University Of Queensland , University Of Southern California , Stanley Family Foundation , Robert Wood Johnson Foundation , Geisinger Health System ,