PFOB@LIP-Tet to treat dry eye disease
8 Cytokines, including Il-1β, TNF-α, and PEG 2 and VEGF, have been certified to play an important role in DED, and by inhibiting expression of those cytokines, symptoms of DED could be significantly alleviated. 35–39 Traditional anti-inflammatory agents like corticosteroids would result in disastrous incidence if inappropriately applied, including intraocular hypertension and cataract, 10 which narrows its use in DED therapy. Therefore, an effective anti-inflammation agent with less impact on intraocular pressure is worthy of exploration. Tet, a plant alkaloid isolated from a traditional ...
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