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Life-cycle-coupled evolution of mitosis in close relatives of animals

Eukaryotes have evolved towards one of two extremes along a spectrum of strategies for remodelling the nuclear envelope during cell division: disassembling the nuclear envelope in an open mitosis or constructing an intranuclear spindle in a closed mitosis1,2. Both classes of mitotic remodelling involve key differences in the core division machinery but the evolutionary reasons for adopting a specific mechanism are unclear. Here we use an integrated comparative genomics and ultrastructural imaging approach to investigate mitotic strategies in Ichthyosporea, close relatives of animals and fungi. We show that species in this clade have diverged towards either a fungal-like closed mitosis or an animal-like open mitosis, probably to support distinct multinucleated or uninucleated states. Our results indicate that multinucleated life cycles favour the evolution of closed mitosis. We analyse cell division in ichthyosporeans and find that multinucleated life cycles favour the evolution of clos ....

Comunidad Autonoma De Cataluna , Wohlwend Gmb , Ted Pella , Imod Etomo , Biowave Ted Pella , Fiji Software Image , Fiji Software , Hidden Markov , Extended Data , Instant Ocean , Alexa Fluor , Chem Cruz , Airyscan Fast , Santa Cruz Biotechnology , Stemcell Technologies , Analyse Skeleton , Graphpad Prism , Supplementary Videos , Supplementary Video , Abra Fluid , Wohlwend Gmbh , Thermofisher Scientific , Whitneyu Test ,

Where Are They Now SQZ Biotech

Where Are They Now SQZ Biotech
lifescienceleader.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from lifescienceleader.com Daily Mail and Mail on Sunday newspapers.

Andrea Adamo , Bob Langer , Klavs Jensen , Ben Comer , Chief Editor , Life Science , Life Science Leader , Professor Klavs Jensen , Stemcell Technologies , Portal Biotechnologies ,

FDA approves B.C. made diagnostic tool for multiple myeloma - Bowen Island Undercurrent

FDA recognizes cell enrichment process, paving the way for more Stemcell diagnostic kits. ....

United States , British Columbia , Ann Lewis , Drug Administration , Stemcell Technologies ,

FDA approves B.C. made diagnostic tool for multiple myeloma

FDA approves B.C. made diagnostic tool for multiple myeloma
newwestrecord.ca - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from newwestrecord.ca Daily Mail and Mail on Sunday newspapers.

British Columbia , United States , Ann Lewis , Drug Administration , Stemcell Technologies ,

FDA approves B.C. made diagnostic tool for multiple myeloma

FDA recognizes cell enrichment process, paving the way for more Stemcell diagnostic kits. ....

British Columbia , United States , Ann Lewis , Drug Administration , Stemcell Technologies ,