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Silenced p16 gene can drive colorectal cancer progression

Colorectal cancer is the fourth most common and second deadliest cancer. How colorectal cancer develops is not well understood, but a team led by researchers at Baylor College of Medicine reports in the Journal of Experimental & Clinical Cancer Research that silencing the gene p16, even though the DNA itself does not change, can drive colorectal cancer progression in animal models. ....

United States , Ya Cui , Xiaomin Chen , Lanjing Zhang , Jingyi Jessica Li , Jiejun Shi , Li Yang , Emilyb Lawrence , Sumimasa Arimura , Yumei Li , Lanlan Shen , Los Angeles , Nan Gao , Emily Henderson , Hyun Jung , Wei Li , Christy Lee , Journal Of Experimental Clinical Cancer Research , University Of California , Us Department Of Agriculture , Princeton Medical Center , Rutgers University , Baylor College Of Medicine , National Institutes Of Health , Baylor College , Clinical Cancer Research ,