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Renal denervation lowered blood pressure out to 36 months, regardless of baseline antihypertensive class combinations and polypharmacy burden, according to an analysis of the Global SYMPLICITY Registry DEFINE.At 36 months, 31% of participants decreased the number of antihypertensive drug classes, according to the study published in Hypertension.
The new analysis has several limitations, but Deepak Bhatt says it provides reassurances about the durability of the procedure.
Although interest in renal denervation in hypertension fell off after disappointing results from the 2014 trial, a new, longer-term analysis argues the treatment may have 'worked' after all.
Experts grappled with how to understand the positive findings given that the trial missed its primary endpoint at 6 months.
Experts grappled with how to understand the positive findings given that the trial missed its primary endpoint at 6 months.