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Pre-Op Immunotherapy Combo Makes Headway in Select Gastric Cancers - Vimarsana News

Pre-Op Immunotherapy Combo Makes Headway in Select Gastric Cancers

Plus, novel bispecific antibody tested as first-line therapy for advanced gastric/GEJ cancer

Casablanca Drops Handmade Surfboards for SS21 - Vimarsana News

Casablanca Drops Handmade Surfboards for SS21

Surfs Up: Casablanca Drops Bespoke Surfboards and Swimwear: One-of-a-kind boards emblazoned with thematic patterns.

Europe approves KEYTRUDA as first-line colorectal cancer therapy - Vimarsana News

Europe approves KEYTRUDA as first-line colorectal cancer therapy

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Merck & Co., Inc.: European Commission Approves KEYTRUDA (pembrolizumab) as First-Line Treatment in Adult Patients With Metastatic Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Colorectal Cancer - Vimarsana News

Merck & Co., Inc.: European Commission Approves KEYTRUDA (pembrolizumab) as First-Line Treatment in Adult Patients With Metastatic Microsatellite Instability-High (MSI-H) or Mismatch Repair Deficient (dMMR) Colorectal Cancer

(2) KEYTRUDA Is First Checkpoint Inhibitor Approved in Europe to Treat MSI-H or dMMR Colorectal Cancer European Approval Based on Results From KEYNOTE-177 Trial Demonstrating KEYTRUDA Significantly Reduced Risk of Disease Progression or Death by 40% Compared With Chemotherapy Merck (NYSE: MRK), known as MSD outside the United States and Canada, announced today that the European Commission has approved KEYTRUDA, Merck's anti-PD-1 therapy, as a monotherapy for the first-line treatment of adult patients with metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) ...

New Anti-PD-1 Drug Active in Advanced Colon Cancer - Vimarsana News

New Anti-PD-1 Drug Active in Advanced Colon Cancer

This article is a collaboration between MedPage Today and: Almost 40% of progressive, advanced gastrointestinal (GI) tumors with mismatch repair deficiency (dMMR) responded to the investigational anti-PD-1 agent dostarlimab, according to a preliminary clinical trial. Overall, 38.7% of 106 patients responded to single-agent treatment with monoclonal antibody, including 36.2% of colorectal cancers (CRC) and 43.2% of all other tumors, which were primarily GI in origin. About three-fourths of patients had some degree of tumor shrinkage. During a median follow-up exceeding 1 year, median duration...