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A2B530 Harnesses Unique Mechanism of Action to Integrate CAR T in Solid Tumors

Looking to replicate the impressive findings with CAR T-cell therapies observed in patients with hematologic malignancies, investigators have initiated the BASECAMP-1 trial with the hope of identifying patients with advanced solid tumors who will be suitable candidates for treatment in the EVEREST trial. ....

United States , New York , Kedar Kirtane , Dianem Simeone , Department Of Head , Perlmutter Cancer Center , Society For Immunotherapy Of Cancer , Pancreatic Cancer Center , Endocrine Oncology At Moffitt Cancer Center , Neck Endocrine Oncology , Moffitt Cancer Center , Annual Meeting , Tmodt Cell , Accessed April , Cart Cell Therapies Observed In Patients With Hematologic Malignancies , Basecamp 1 Trial , Patients With Advanced Solid Tumors , Everest Trial ,

EVEREST-1 Trial Seeks to Bring HLA-A*02-directed CAR T to Patients With Solid Tumors

The upcoming phase 1/2 EVEREST-1 trial, where the novel CAR T-cell therapy A2B530 will be evaluated in patients with solid tumors, aims to push progress for one-and-done engineered therapies in this space. ....

United States , New York , Dianem Simeone , Pancreatic Cancer Center , Perlmutter Cancer Center , Tmodt Cell , Everest 1 Trial , Hlaa 02 Directed Cart Cell Therapy , Solid Tumors ,

BASECAMP-1 Aims to Identify Patients Eligible for Treatment With Novel CAR T-Cell Agent

Looking to replicate the impressive findings with CAR T-cell therapies observed in patients with hematologic malignancies, investigators have initiated the BASECAMP-1 trial, with the hope of identifying patients with advanced solid tumors who will be suitable candidates for treatment in a subsequent trial evaluating the investigational agent A2B530. ....

United States , Marwang Fakih , Judy Bernard Briskin , J Randolph Hecht , David Geffen School Of Medicine , Gastrointestinal Gi Oncology Program , Gastrointestinal Cancer Program , Department Of Medical Oncology Therapeutics Research , Clinical Research At City Of Hope , Medical Oncology , Therapeutics Research , Bernard Briskin Distinguished Director , Clinical Research , Oncology Program , David Geffen School , Tmodt Cell , Cart Cell Therapy , Asecamp 1 Trial Nct04981119 , City Of Hope Duarte , Advanced Solid Tumors ,