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Ribociclib Plus Endocrine Therapy Meets iDFS End Point in HR+ Early Breast Cancer

The combination of ribociclib and endocrine therapy (ET) significantly reduced the risk of disease recurrence vs standard adjuvant ET in patients with hormone receptor–positive/HER2-negative early breast cancer at risk of recurrence. ....

United States , Dennisj Slamon , Shreeram Aradhye , Translational Research In Oncology , Los Angeles Jonsson Comprehensive Cancer Center , University Of California , Clinical Translational Research , Data Monitoring Committee , Global Drug Development , Independent Data Monitoring Committee , Translational Research , Standardized Definitions , Efficacy End Points , Breast Cancer , Early Breast Cancer ,

NATALEE (TRIO033) Phase III trial demonstrates ribociclib significantly reduces the risk of recurrence for patients with early breast cancer, at interim analysis

NATALEE (TRIO033) Phase III trial demonstrates ribociclib significantly reduces the risk of recurrence for patients with early breast cancer, at interim analysis
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United States , Dennisj Slamon , Catherine Marle , Los Angeles Jonsson Comprehensive Cancer Center , Translational Research In Oncology , Clinical Translational Research , University Of California , Research In Oncology , Translational Research , Executive Director ,

High Response Rates With T-DXd in Early HER2-Low Breast Cancer

"The study provides a rich platform for additional translational research to evaluate more sensitive methods of HER2 detection." ....

United States , San Antonio , Jasona Mouabbi , Aditya Bardia , Daiichi Sankyo , Eli Lilly , Fresenius Kabi , University Of Texas Md Anderson Cancer Center , Hospital Cancer Center , Translational Research In Oncology , Napo Pharmaceuticals , Cardinal Health , Radius Health , Immunomedics Gilead Sciences , Massachusetts General Hospital Cancer Center , Antonio Breast Cancer , Cancer Center , Gilead Sciences , Breast Cancer , Alignant Breast Neoplasm , Biologic Therapy , Alignant Neoplasia , Antineoplastic Drug , Nti Cancer Agents , Translational Research , Ranslative Research ,

Study reports overall response of HER2-low breast cancer patients to neoadjuvant T-DXd treatment

Patients with localized, hormone receptor-positive, HER2-low breast cancer treated with trastuzumab deruxtecan (T-DXd, Enhertu) in the neoadjuvant setting had an overall response rate of 75 percent in the absence of anastrozole and 63 percent in combination with anastrozole, according to results from the phase II TRIO-US B-12 TALENT trial presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022. ....

United States , San Antonio , Sara Hurvitz , Los Angeles , Aditya Bardia , Daiichi Sankyo , Genentech Roche , Eli Lilly , Emily Henderson , University Of California , Merrimack Pharmaceuticals , Translational Research In Oncology , Radius Health , Gilead Sciences , Drug Administration , Cancer Center , Harvard Medical School , Pieris Pharmaceuticals , Division Of Hematology Oncology , Immunomedics Gilead Sciences , San Antonio Breast Cancer Symposium , Mass General Cancer Center , Harvard Medical , Clinical Research Unit , Jonsson Comprehensive Cancer Center , Discovery Industry Focus ,

Xtalks Announces its Life Science Webinar Calendar for December 2022

Toronto, ON (PRWEB) December 07, 2022 Stay on top of current hot topics through free webinars presented by leading experts in the pharma, biotech, medical ....

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