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Doses? >> announcer: nbc nightly news with lester holt. finally a big change finally a big change coming to the super bowl, jo lynn kent, on why big advertisers are taking a time out. >> reporter: for the first time in 37 years, budweiser is benching their shot in a viral super bowl ad, saying instead they'll pass some of that air time onto vaccine awareness campaigns for the pandemic >> let's turn our strength into hope >> reporter: how different are ads going to look this year overall? >> it is a tricky year to hit the tone and decide people ready for a laugh or something serious? >> rep...

The number of fans won't be the only thing scaled back at this year's super bowl, when the kansas city chiefs take on the buccaneers. as nbc news correspondent joy lynn kent reports for us, several big-name advertisers are sitting out the game. >> reporter: first time in 37 years, budweiser is benching their shot at a viral super bowl

The number of fans won't be the only things scaled back when the kansas city chiefs take on the buccaneers. several big-named avertisers have decided to sit out this game. >> reporter: for the first time in 37 years. >> was up. >> reporter: budweiser is saying instead they'll pass some of the air time on to vaccine awareness campaign for the pandemic. >> let's turn our strength into hope. how different are ads going to look this year overall? >> a tricky year to hit the tone and decide are people ready for a laugh or do they want something more serious? >> reporter: coke, pepsi and hyundai are...

This is a king toad. those are poison glands. this came over from south america and we brought it into this country, southern florida. it's causing a lot of deaths with dogs. these are poison glands right back there. >> get it away from me. get it off me! >> it's just a toad. >> it's okay. >> i don't like toads much, i don't like them either. >> you're okay. he didn't bite. >> get it out of here.