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Antibody Prevents Gastrointestinal GVHD without Broad Immunosuppression

Antibody Prevents Gastrointestinal GVHD without Broad Immunosuppression
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United States , Leslies Kean , Ivan Maillard , Harvard Medical School , University Of Pennsylvania , Perelman School Of Medicine , Blood Disorders Center , Penn Medicine , Boston Children , Perelman School , Science Translational Medicine , Victor Tkachev Phd , Mass General Brigham ,

Experimental antibody treatment shows promise for preventing bone marrow transplant complication

An experimental antibody treatment largely prevented a bone marrow transplant complication called graft versus host disease (GVHD) in the intestines, without causing broad immune suppression, in a preclinical study led by researchers from Penn Medicine and Dana-Farber/Boston Children's Cancer and Blood Disorders Center and published today in Science Translational Medicine. ....

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