Stay updated with breaking news from Vilas Menon. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.
Genetic detective work by Brigham researchers sheds light on a promising new treatment strategy for Alzheimer’s disease. Alzheimer’s disease (AD) manifests with a broad spectrum of age onset, symptoms, and severity levels. Lately, the SORL1 gene has garnered interest due to its links with both earl
11 Dec 2020 It is difficult to isolate large quantities of microglia from human brain. That’s why scientists still know little about the different ways these cells rear up in health and disease. A new single-cell—not single-nucleus—RNA-sequencing study led by Philip De Jager at Columbia University, New York, sheds some light on this. It analyzed the largest number of microglia yet, totaling more than 16,000, isolated from the brains of people with Alzheimer’s disease and normal cognition. In the November 30 Nature Communications, the authors describe nine distinct transcriptional stat...