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Date Time Nanobodies inhibit SARS-CoV-2 infection Australian researchers have identified neutralising nanobodies that block the SARS-CoV-2 virus from entering cells in preclinical models. The discovery paves the way for further investigations into nanobody-based treatments for COVID-19. Visualisation of SARS-CoV-2 virus with nanobodies (purple) attaching to the virus ‘spike’ protein. Image: Dr Drew Berry in collaboration with Associate Professor Wai-Hong Tham Published in PNAS, the research is part of a consortium-led effort, bringing together the expertise of Australian academic leaders ...

Overview The Clinton Health Access Initiative, Inc. (CHAI) is a global health organization committed to saving lives and reducing the burden of disease in low-and middle-income countries, while strengthening the capabilities of governments and the private sector in those countries to create and sustain high-quality health systems that can succeed without our assistance. For more information, please visit: http://www.clintonhealthaccess.org CHAI began work in Cameroon in 2007, with a focus on improving access to lifesaving HIV diagnosis, treatment, and care. CHAI helped the Ministry of Health ...

What We Know About SARS-CoV-2 One Year Later: Part 2 Sponsored Content by ACROBiosystemsApr 14 2021 The S protein of SARS-CoV had been studied extensively before the SARS-CoV-2 outbreak. Among other structural proteins of SARS-CoV-2, the S protein was discovered to be highly immunogenic and effective at neutralizing antibodies recovered from SARS patients were directed at S protein. 6,7 Research into therapeutics and vaccines against SARS-CoV-2 was focused immediately on the S protein. Although the four structural proteins of the novel SARS-CoV share over 90% in sequence identity with SARS-Co...

Dr Sujay Prasad, Medical Director, Neuberg Anand Reference Laboratory, said that the decision by ICMR to decide on a cut-off Ct value will impact a small number of cases that may have been positive as per the manufacturer, but negative as per the new cut-off. The negatives will not be impacted and hence the false negatives are likely to be higher.

University of Bristol University of Bristol A team of top scientists from the University of Bristol have announced the formation of a new biotech company that is developing ground-breaking and newly patented potential treatments for coronavirus. Halo Therapeutics Ltd is preparing for clinical trials into pivotal, cost-effective antiviral treatments for COVID-19, after discovering a molecule which changes the shape of the virus’s spike protein and in so doing inhibits the virus’ ability to enter cells. Studies show the treatments are pote...