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Study Shows New Approach to Target Deadly Form of Prostate Cancer

Study Shows New Approach to Target Deadly Form of Prostate Cancer
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Unraveling biology behind aggressive pediatric brain tumor reveals potential new treatment avenue

Unraveling biology behind aggressive pediatric brain tumor reveals potential new treatment avenue
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United States , Fernandom Nunez , Kaushik Banerjee , Maria Vinci , Visweswaran Ravikumar , Stephen Carney , Caitlin Alindogan , Maria Castro , Justin Dreyer , Sriram Venneti , Padma Kadiyala , Sarah Thompson , Angelm Carcaboso , Felipej Nunez , Jennifers Yu , Mariab Garcia Fabiani , Arvind Rao , Ayman Taher , Anzar Abdul Mujeeb , Marcusn Barissi , Richardc Schneider , Emily Brumley , Pedro Lowenstein , Mahmouds Alghamri , Carson Hartlage , Carl Koschmann ,

A new, vital player in graft-versus-host disease and organ transplant rejection

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A long noncoding RNA whose function was previously unknown turns out to play a vital role in mobilizing the immune response following a bone marrow transplant or solid organ transplantation.
This RNA molecule, cataloged in scientific databases simply as Linc00402, helps activate immune defenders known as T cells in response to the presence of foreign human cells, according to a new study by researchers at the University of Michigan Rogel Cancer Center and Michigan Medicine.
The investigation, which included samples from more than 50 patients who underwent a bone marrow or heart transplant, suggests inhibiting the RNA therapeutically might improve outcomes for transplant recipients. Their findings appear in ....

Michigan Center , United States , Cynthia Zajac , Julia Wu , Guoqing Hou , Visweswaran Ravikumar , Hideaki Fujiwara , Austin Taylor , Daniel Goldstein , Stephanie Kim , Molly Radosevich , Sherric Wood , Thomas Decoville , David Sokol , Arvind Rao , Pavan Reddy , Yaping Sun , Arul Chinnaiyan , Katherine Oravecz Wilson , Daniel Peltier , Sethuramasundaram Pitchiaya , Baldrick Foundation Fellowship , National Institutes Of Health , Rogel Cancer Center , University Of Michigan Rogel Cancer Center , Department Of Defense Idea Development Award ,

A new, vital player in graft-versus-host disease and organ transplant rejection

A new, vital player in graft-versus-host disease and organ transplant rejection
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Michigan Center , United States , Cynthia Zajac , Julia Wu , Guoqing Hou , Visweswaran Ravikumar , Hideaki Fujiwara , Austin Taylor , Daniel Goldstein , Stephanie Kim , Molly Radosevich , Sherric Wood , Thomas Decoville , David Sokol , Arvind Rao , Pavan Reddy , Yaping Sun , Arul Chinnaiyan , Katherine Oravecz Wilson , Daniel Peltier , Sethuramasundaram Pitchiaya , Baldrick Foundation Fellowship , National Institutes Of Health , Rogel Cancer Center , University Of Michigan Rogel Cancer Center , Department Of Defense Idea Development Award ,