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FDA Grants Breakthrough Therapy Designation to BNT323/DB-1303 in Endometrial Cancer

The FDA has granted breakthrough therapy designation to the HER2-targeted antibody-drug conjugate BNT323/DB-1303 for use as a potential therapeutic option in patients with advanced endometrial cancer who have progressed on or after treatment with immune checkpoint inhibitors. ....

Vivian Gu , Intj Gynecol , The Fda Has Granted Breakthrough Therapy Designation , Her2 Targeted Antibody Drug Conjugate Bnt323 Db 1303 , Patients With Advanced Endometrial Cancer Who Have Progressed On Or After Treatment Immune Checkpoint Inhibitors , Phase 1 2 Trial Nct05150691 ,