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Cancer has been rare among the monarchs who immediately preceded Charles during the 20th century, only one of whom died before the age of 60.
King George VI was a famously reluctant monarch who had acceded unexpectedly to the throne in December 1936. This followed the dramatic abdication of older brother, Edward VIII.
Queen Elizabeth II reigned for 70 years before passing away at the age of 96, but it is unclear whether King Charles will follow in her footsteps or abdicate from the throne in favour of his heir Prince William.
King Charles's cancer diagnosis has sent shockwaves through the nation. A look at Royal Family history shows a number of high-profile names have battled the disease and lived long lives
The monarch is currently still carrying out his constitutional duties after his cancer diagnosis.