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Comparison of surgical modalities in the treatment of Merkel Cell Carcinoma

1. Mohs micrographic surgery was associated with significantly higher survival rates for patients with T1/T2 Merkel cell carcinoma with pathologically confirmed negative lymph nodes compared to other surgical modalities (i.e., wide local excision and narrow-margin excision). 2. Mohs micrographic surgery may be a more effective treatment for primary Merkel cell carcinoma than conventional wide-local excision. ....

National Comprehensive Cancer Network , National Cancer Database , Rating Level , Merkel Cell Carcinoma Mcc , Mohs Micrographic Surgery Mms , Wide Local Excision ,

Narrow margin excision of T1a melanoma not associated with recurrence or melanoma-specific mortality

1. Wide local excision of T1a melanoma near critical structures with narrow (5-mm) margins was not associated with worse outcomes. 2. Fewer reconstructive surgeries were found in wide local excision of T1a melanoma near critical structures with narrow (5-mm) compared to wide (10-mm) margins. Evidence Rating Level: 2 (Good) Study Rundown: Surgical excision is recommended ....

National Cancer Insitute , Rating Level , Acral Lentiginous Melanoma , Malignant Melanoma , Narrow Margin Excision , T1a Melanoma , Wide Local Excision ,