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T Cells Engineered To Attack a Variety of Cancers

Control mice (left panel) with prostate cancer show large areas of metastasis in the lungs (blue). When a subset of animals were treated with unmodified T cells (middle panel), the secondary tumors were smaller than in untreated mice. And when a separate group of mice received T cells engineered to produce MDA-7/IL-24 (right panel), metastases shrunk even more, in some cases down to nothing. Credit: Shawn Wang, PhD
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Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it s possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues. This research will be published in tomorrow s print edition of Cancer Research. ....

Xiang Yang Shawn Wang , Thelma Newmeyer Corman , Paulb Fisher , Cancer Research , Virginia Commonwealth University Massey Cancer Center , School Of Medicine , National Cancer Institute , Institute Of Molecular Medicine , Department Of Human , Oncology Research , Cancer Biology , Developmental Therapeutics , Molecular Genetics , Molecular Medicine , Thelma Newmeyer Corman Endowed Chair , Judy Wason Distinguished Professorship , புற்றுநோய் ஆராய்ச்சி , வர்ஜீனியா காமன்வெல்த் பல்கலைக்கழகம் மஸ்ஸி புற்றுநோய் மையம் , பள்ளி ஆஃப் மருந்து , தேசிய புற்றுநோய் நிறுவனம் , நிறுவனம் ஆஃப் மூலக்கூறு மருந்து , துறை ஆஃப் மனிதன் , புற்றுநோயியல் ஆராய்ச்சி , புற்றுநோய் உயிரியல் , வளர்ச்சி சிகிச்சை , மூலக்கூறு ஜெநெடிக்ஸ் ,

Study focuses on engineering T cells to attack cancer broadly

Study focuses on engineering T cells to attack cancer broadly
ANI |
Updated: May 01, 2021 08:27 IST
Richmond (Virginia) [United States], May 1 (ANI): Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it s possible to arrest tumour growth for a variety of cancers and squash the spread of cancer to other tissues.
This research will be published in the journal Cancer Research.
The paper builds on decades of research by study co-senior author Paul B. Fisher, M.Ph., Ph.D., a member of Massey s Cancer Biology research program, who discovered a protein called IL-24 that attacks a variety of cancers in several different ways. ....

Virginia Commonwealth University Massey Cancer Center , United States , Xiang Yang Shawn Wang , Thelma Newmeyer Corman , Paulb Fisher , Cancer Research , School Of Medicine , National Cancer Institute , Institute Of Molecular Medicine , Department Of Human , Oncology Research , Cancer Biology , Developmental Therapeutics , Molecular Genetics , Molecular Medicine , Thelma Newmeyer Corman Endowed Chair , Judy Wason Distinguished Professorship , T Cell , Ttack Cancer Broadly , Da 7 Il 24 , Ostate Cancer Or Melanoma , Latest Health Related Study , வர்ஜீனியா காமன்வெல்த் பல்கலைக்கழகம் மஸ்ஸி புற்றுநோய் மையம் , ஒன்றுபட்டது மாநிலங்களில் , புற்றுநோய் ஆராய்ச்சி , பள்ளி ஆஃப் மருந்து ,

Arresting tumor growth for a variety of cancers through T cell engineering

Arresting tumor growth for a variety of cancers through T cell engineering
Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it s possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues. This research will be published in tomorrow s print edition of
Cancer Research.
The paper builds on decades of research by study co-senior author Paul B. Fisher, M.Ph., Ph.D., a member of Massey s Cancer Biology research program, who discovered a protein called IL-24 that attacks a variety of cancers in several different ways. ....

Xiang Yang Shawn Wang , Thelma Newmeyer Corman , Paulb Fisher , Emily Henderson , Cancer Research , Virginia Commonwealth University Massey Cancer Center , School Of Medicine , National Cancer Institute , Institute Of Molecular Medicine , Department Of Human , Oncology Research , Cancer Biology , Developmental Therapeutics , Molecular Genetics , Molecular Medicine , Thelma Newmeyer Corman Endowed Chair , Judy Wason Distinguished Professorship , Prostate Cancer , எமிலி ஹென்டர்சன் , புற்றுநோய் ஆராய்ச்சி , வர்ஜீனியா காமன்வெல்த் பல்கலைக்கழகம் மஸ்ஸி புற்றுநோய் மையம் , பள்ளி ஆஃப் மருந்து , தேசிய புற்றுநோய் நிறுவனம் , நிறுவனம் ஆஃப் மூலக்கூறு மருந்து , துறை ஆஃப் மனிதன் , புற்றுநோயியல் ஆராய்ச்சி ,

Engineering T cells to attack cancer broadly

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IMAGE: Control mice (left panel) with prostate cancer show large areas of metastasis in the lungs (blue). When a subset of animals were treated with unmodified T cells (middle panel), the.
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Credit: Shawn Wang, Ph.D.
Through T cell engineering, researchers at Virginia Commonwealth University Massey Cancer Center show that it s possible to arrest tumor growth for a variety of cancers and squash the spread of cancer to other tissues. This research will be published in tomorrow s print edition of
Cancer Research.
The paper builds on decades of research by study co-senior author Paul B. Fisher, M.Ph., Ph.D., a member of Massey s Cancer Biology research program, who discovered a protein called IL-24 that attacks a variety of cancers in several different ways. ....

Ranjan Pradhan , Jolene Windle , Chunqing Guo , Zheng Liu , Xiaofei Yu , Xiang Yang Shawn Wang , Shixian Chen , Swadesh Das , Xia Li , Wenjie Liu , Thelma Newmeyer Corman , Paulb Fisher , Masoud Manjili , Massey Cancer Center Research Development Funds , School Of Medicine , National Cancer Institute , Institute Of Molecular Medicine , Department Of Human , Oncology Research , Virginia Commonwealth University Massey Cancer Center , Cancer Research , National Foundation For Cancer Research , Massey Cancer Center , Department Of Defense Prostate Cancer Research Program , Cancer Center Support Grant , Cancer Biology ,