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UT Southwestern's cryo-EM images shed light on the mechanisms behind Wnt signaling activation

Using UT Southwestern's Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation. ....

United States , Boyuan Wang , Nadia Elghobashi Meinhardt , Xiaofeng Qi , Yingyuan Sun , Yang Liu , Emily Henderson , Williamp Clements Jr , Xiaochun Li , Linda Donnelly , National Institutes Of Health , Ut Southwestern Medical Center Facility , Technical University Berlin , Welch Foundation , Damon Runyon Cancer Foundation , Scholar In Biomedical Research , Life Sciences Research Foundation , Research Institute Of Texas , Cryo Electron Microscopy Facility , Associate Professor , Molecular Genetics , Tao Long , National Institutes , Life Sciences Research , Cancer Prevention , Research Institute ,

New cryo-EM images shed light on Wnt signaling

New cryo-EM images shed light on Wnt signaling
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United States , Boyuan Wang , Nadia Elghobashi Meinhardt , Xiaofeng Qi , Yingyuan Sun , Yang Liu , Williamp Clements Jr , Xiaochun Li , Linda Donnelly , National Institutes Of Health , Ut Southwestern Medical Center Facility , Technical University Berlin , Welch Foundation , Damon Runyon Cancer Foundation , Scholar In Biomedical Research , Life Sciences Research Foundation , Research Institute Of Texas , Cryo Electron Microscopy Facility , Associate Professor , Molecular Genetics , Tao Long , National Institutes , Life Sciences Research , Cancer Prevention , Research Institute , Porcupine Mediated Wnt ,