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Devastating liver disease itching turns out to have a surprising cause


Devastating liver disease itching turns out to have a surprising cause
A devastating itching of the skin driven by severe liver disease turns out to have a surprising cause. Its discovery points toward possible new therapies for itching, and shows that the outer layer of the skin is so much more than insulation.
The finding, which appears April 2 in
Gastroenterology, indicates that the keratinocyte cells of the skin surface are acting as what lead researcher Wolfgang Liedtke, MD PhD, calls pre-neurons.
The skin cells themselves are sensory under certain conditions, specifically the outermost layer of cells, the keratinocytes.
Wolfgang Liedtke, Professor of Neurology, Duke School of Medicine ....

Wolfgang Liedtke , Yong Chen , Emily Henderson , Rockefeller University , Duke School Of Medicine , Wake Forest University , Duke School , ஓநாய் லிெடுட்கே , யோங் சென் , எமிலி ஹென்டர்சன் , ராக்ஃபெல்லர் பல்கலைக்கழகம் , டியூக் பள்ளி ஆஃப் மருந்து , எழுந்திரு காடு பல்கலைக்கழகம் , டியூக் பள்ளி ,

How a moving platform for 3D printing can cut waste and costs


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IMAGE: A NEW DYNAMICALLY-CONTROLLED BASE FOR 3-D PRINTING (LEFT) WILL REDUCE THE NEED FOR PRINTED SUPPORTS (CENTER), CUTTING WASTAGE AND SAVING TIME.
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Credit: Yong Chen
3-D printing has the potential to revolutionize product design and manufacturing in a vast range of fields from custom components for consumer products, to 3-D printed dental products and bone and medical implants that could save lives. However, the process also creates a large amount of expensive and unsustainable waste and takes a long time, making it difficult for 3-D printing to be implemented on a wide scale.
Each time a 3-D printer produces custom objects, especially unusually-shaped products, it also needs to print supports­-printed stands that balance the object as the printer creates layer by layer, helping maintain its shape integrity. However, these supports must be manually removed after printing, which requires finishing by hand and can result in shape i ....

Siyu Gong , Yang Xu , Yong Chen , Ziqi Wang , Viterbi Danielj Epstein Department Of Industrial , School Of Computer , Communication Sciences , Systems Engineering , Fused Deposition Modeling , யாங் ஐயூ , யோங் சென் , பள்ளி ஆஃப் கணினி , தொடர்பு அறிவியல் , அமைப்புகள் பொறியியல் , இணைந்தது படிவு மாடலிங் ,

Dynamic additive platform prints using movable supports


6th April 2021
10:48 am
6th April 2021
10:48 am
Engineers in the US have created a prototype 3D printing platform with adjustable metal pins that negate the need to print excess support structures.
Many additive methods rely on printing additional support material in order to maintain part integrity during the manufacturing process, particularly for complex components. These excess structures must then be removed and the part finished by hand, something that can result in shape inaccuracies or surface roughness. Furthermore, the additional material can often not be reused, leading to increased waste.
The new platform, developed by scientists at the USC Viterbi School of Engineering, features programmable, dynamically controlled metal pins to replace the printed supports. According to the researchers, testing of the prototype demonstrated around a 35 per cent saving in the materials required to print certain parts. ....

Yong Chen , Viterbi School Of Engineering , Fused Deposition Modelling , யோங் சென் , விட்டர்பி பள்ளி ஆஃப் பொறியியல் , இணைந்தது படிவு மாடலிங் ,

Dynamic platform cuts 3D printing waste by 35%


Dynamic platform cuts 3D printing waste by 35%
06 Apr 2021
Professional Engineering
The dynamically controlled surfaces (a) reduce the need for printed supports (b) to cut waste material (Credit: Yong Chen)
A dynamically controlled surface with moving metal platforms can cut material usage in 3D printing by reducing the need for “wasteful” printed supports, its developers have said.
Printing times could also be shortened thanks to the new technique, said the researchers from the University of Southern California (USC).
As conventional 3D printers create custom objects layer-by-layer, they often need to print supports to balance the product. These supports are manually removed after printing, which requires finishing by hand and can result in shape inaccuracies or surface roughness. The materials the supports are made from often cannot be reused, so they are discarded and contribute to the growing problem of 3D-printed waste materi ....

Siyu Gong , Yang Xu , Yong Chen , Ziqi Wang , University Of Southern California , Southern California , Fused Deposition Modelling , Professor Yong , யாங் ஐயூ , யோங் சென் , பல்கலைக்கழகம் ஆஃப் தெற்கு கலிஃபோர்னியா , தெற்கு கலிஃபோர்னியா , இணைந்தது படிவு மாடலிங் , ப்ரொஃபெஸர் யோங் ,