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Estrogen-Regulated Brain Circuit Helps Females Control Obesity

The estrogen-regulated brain circuit begins in neurons located in a region of the hypothalamus called the ventrolateral subdivision of the ventromedial hypothalamic nucleus. The circuit not only responds to estrogen, but also to changes in ambient temperature and in the nutritional status of the animal. Interestingly, the circuit seems to be functional in males but, at this point, its physiological relevance is not clear. ....

Yong Xu , Baylor College Of Medicine , Baylor College , Science Advances ,

Estrogen-activated neurocircuit in females provide anti-obesity benefits

Seeking to better understand the key role the female hormone estrogen plays in maintaining energy balance and weight control, a group led by researchers at Baylor College of Medicine looked into estrogen interactions with specific brain regions that provide these anti-obesity benefits. ....

Yong Xu , Emily Henderson , Baylor College Of Medicine , Baylor College , Science Advances , Co Corresponding Author , Cellular Biology , Physical Activity ,