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Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls. ....

Emily Henderson , Youyang Zhao , Division Of Critical Care , Cell Reports , Critical Care , Yang Zhao , Stanley Manne Children , Research Institute , Blood Vessel , Genome Editing , Critical Care ,

Unique nanoparticle can deliver genome editing technology to endothelial cells

The lab of Youyang Zhao, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which are cells that line blood vessel walls. ....

Youyang Zhao , Emily Henderson , Stanley Manne Children , Research Institute , Lurie Children , Blood Vessel , Genome Editing ,

Novel System Developed for Genome Editing in Vascular Endothelial Cells

A new study in mice demonstrates how vascular endothelial cells could be reached through genome editing to help treat diseases such as acute respiratory distress syndrome or severe COVID-19. ....

Youyang Zhao , Cell Reports , Stanley Manne Children , Research Institute ,