Stay updated with breaking news from Zeiss Elyra. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.
Zeiss, a pioneer in microscopy solutions, is introducing an innovative addition to its product portfolio with the Zeiss Lattice SIM product family. Click to read more...
Lattice SIM product family operates across all scales and applications.
Senescent cells drive age-related tissue dysfunction partially through the induction of a chronic senescence-associated secretory phenotype (SASP)1. Mitochondria are major regulators of the SASP; however, the underlying mechanisms have not been elucidated2. Mitochondria are often essential for apoptosis, a cell fate distinct from cellular senescence. During apoptosis, widespread mitochondrial outer membrane permeabilization (MOMP) commits a cell to die3. Here we find that MOMP occurring in a subset of mitochondria is a feature of cellular senescence. This process, called minority MOMP (miMOMP)...