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2021 Szent-Györgyi Prize Awarded to Pioneering Research Duo Who Have Paved the Path to Life-Saving T-Cell Receptor-Based Cancer Immunotherapies


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ROCKVILLE, Md., Feb. 18, 2021 /PRNewswire/  The National Foundation for Cancer Research (NFCR) announced today that the 2021 Szent-Györgyi Prize for Progress in Cancer Research will be awarded to Tak W. Mak, Ph.D., senior scientist at the Princess Margaret Cancer Centre and university professor at the University of Toronto, and Mark M. Davis, Ph.D., professor of microbiology and immunology at the Stanford University School of Medicine, for their breakthrough discoveries of the structure of T-cell receptor (TCR) and pioneering research in deciphering the mechanisms of T-cell recognition and development. These discoveries have formed a critical part of contemporary immuno-oncology and the molecular foundation for life-saving CAR (chimeric antigen receptor) T-cell therapies, a novel T-cell-based immunotherapy approach already approved by the U.S. Food and Drug Administration (FDA) for the treatment of several types of blood cancer. ....

University Of Washington , United States , Dana Farber Cancer Institute , Websterk Cavenee , Bradley Gillenwater , Carlom Croce , Johnt Schiller , Mary Claire King , Zhu Chen , Michaeln Hall , Stevena Rosenberg , Douglasr Lowy , Beatrice Mintz , James Allison , Albert Szent , Sujuan Ba , Peterk Vogt , Zhen Yi Wang , Markm Davis , Ronalda Depinho , Haroldf Dvorak , Beth Israel Deaconess Medical Center , Ohio State University , Stanford University School Of Medicine , University Of Basel , University Of Toronto ,