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BioLabs LA at The Lundquist Institute Reaches 100% Capacity

BioLabs LA at The Lundquist Institute Reaches 100% Capacity
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Lundquist investigators in global study expanding genomic research of different ancestries

Credit: The Lundquist Institute
LOS ANGELES (May 31, 2021) Today The Lundquist Institute announced that its investigators contributed data from several studies, including data on Hispanics, African-Americans and East Asians, to the international MAGIC collaboration, composed of more than 400 global academics, who conducted a genome-wide association meta-analysis led by the University of Exeter. Now published in
Nature Genetics, their findings demonstrate that expanding research into different ancestries yields more and better results, as well as ultimately benefitting global patient care. Up to now nearly 87 percent of genomic research of this type has been conducted in Europeans.
We are very excited about contributing to this global study, said Dr. Jerome I. Rotter, Investigator and Director of the Institute for Translational Genomics and Population Sciences at The Lundquist Institute and Professor of Pediatrics and Human Genetics at the Geffen School of Medicin ....

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Lundquist investigator Wei Yan solves longstanding fallopian tube transport debate

Yan research group has solved a longstanding scientific debate about the mechanism underlying the gamete and embryo transport within the Fallopian tube. Using a mouse model where the animals lacked motile cilia in the oviduct, they demonstrated that motile cilia in the very distal end of the Fallopian tube, the infundibulum, are essential for oocyte pickup. The finding was published in the Proceedings of the National Academy of Sciences (PNAS). ....

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Lindquist investigator research on mucormycosis, the deadly 'black fungus'

Credit: The Lundquist Institute
LOS ANGELES (May 13, 2021) The Lundquist Institute today announced that one of its spinoff start-up companies, Vitalex Biosciences, founded by researcher Dr. Ashraf Ibrahim, is producing an antibody that stems the spread of mucormycosis, a deadly fungal infection with an overall mortality rate of 50% and higher. Mucormycosis is an emerging infection caused by exposure to mucor, a mold commonly found in soil, plants, manure, and decaying fruits and vegetables. It affects the sinuses, the brain and the lungs and is life-threatening in diabetic or severely immunocompromised individuals, such as cancer patients. In addition to the >50% death rates, extremely disfiguring surgery is often needed to remove necrotic tissues. ....

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Lundquist investigator Chang's study in JAMA Internal Medicine

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IMAGE: Lundquist Investigator Dr. Dong Chang and his colleagues study on critically ill patients and ICU treatments was published in JAMA Internal Medicine. The study - Evaluation of Time-Limited Trials Among.
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Credit: Courtesy of The Lundquist Institute
LOS ANGELES (April 13, 2021) The Lundquist Institute (TLI) Investigator Dong W. Chang, MD, and his colleagues study on critically ill patients and ICU treatments was published in
JAMA Internal Medicine. The study - Evaluation of Time-Limited Trials Among Critically Ill Patients with Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments - found that training physicians to communicate with family members of critically ill patients using a structured approach, which promotes shared decision-making, improved the quality of family meetings. This intervention was associated with reductions in invasive ICU treatments that prolonged suffering without benefit for p ....

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