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Taltz® Delivers More Cumulative Days with Completely Clear Skin for Adults with Psoriasis Compared to Seven Other Biologics in Novel Network Meta-Analysis

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INDIANAPOLIS, April 23, 2021 /PRNewswire/ Through clinical trial meta-analysis and real-world evidence, Eli Lilly and Company s (NYSE: LLY) Taltz
® (ixekizumab) demonstrated greater success in key measured treatment outcomes compared to other biologics in adults with moderate to severe plaque psoriasis. In the first one-year network meta-analysis based on area under the curve, Taltz showed numerically greater cumulative benefits on completely clear skin over one year compared to seven other biologics, as measured by Psoriasis Area Severity Index (PASI) 100. In three real-world analyses of U.S. claims data ranging from one to three years, patients treated with Taltz stayed on treatment longer, were more adherent to the prescription and had more days on monotherapy compared to the other biologics studied. These results are being presented virtually at the American Academy of Dermatology s Virtual Meeting Experience (AAD VMX), Apr ....

United States , Kevin Hern , Markg Lebwohl , Marlo Scott , Andrew Blauvelt , Eli Lilly , Exchange Commission , American Academy Of Dermatology Virtual Meeting Experience , Oregon Medical Research Center , Icahn School Of Medicine At Mount Sinai , Psoriasis Area Severity Index , American Academy , Virtual Meeting Experience , Lotus Mallbris , Provided Patients , Longest Lasting Complete Skin Clearance , Clinical Therapeutics , Icahn School , Mount Sinai , Helped Patients Stay , Prescribed Treatment , Taltz Took Treatment , More Frequent , Prior Biologic Use Were More Likely , Continue Treatment , Prescribed Compared ,

Redirecting to LEO Pharma Presents Long-Term Safety and Efficacy Data for Tralokinumab in Adults With Moderate-to-Severe Atopic Dermatitis at AAD VMX 2021

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Participants included 1,174 patients from ECZTEND at data cut-off.1 Observed outcomes for all patients enrolled 60 weeks prior to data cut-off (n=513) were analyzed at Week 56.1 At parent-trial baseline, ECZTEND baseline, and Week 56, median EASI score was 26.6, 4.7, and 1.8, respectively.1 At Week 56, IGA and EASI response rates were 49.7% (IGA 0/1), 95.1% (EASI-50), 82.8% (EASI-75), 61.0% (EASI-90), and 79.7% (EASI ≤7). An EASI score of ≤7 corresponds to mild atopic dermatitis.1
At the same 56-week data cut-off, measurements of itch and sleep disruptions due to itch were also reported.1 At Week 56, the mean worst weekly pruritus (i.e. itch) numeric rating scale (NRS) score was 3.3 (parent-trial baseline was 7.7) while the mean eczema-related weekly sleep NRS score was 2.0 (parent-trial baseline was 6.9).1 ....

United States , Andrew Blauvelt , Oregon Medical Research Center , American Academy Of Dermatology Virtual Meeting Experience , Global Research , National Library Of Medicine , European Medicines Agency On , Committee For Medicinal Products Human Use , American Academy , Dermatology Virtual Meeting Experience , Investigator Global Assessment , Eczema Area , Severity Index , Executive Vice President , Medicinal Products , Human Use , European Medicines Agency , Term Extension , Improvements Observed , Tralokinumab Treatment , Moderate To Severe Atopic Dermatitis , Interim Readout , Long Term Extension , Long Term Extension Trial , Subjects With Atopic Dermatitis Who Participated , Previous Tralokinumab Trials ,

OLUMIANT® Showed Significant Improvements in the Severity and Extent of Atopic Dermatitis and Other Patient-Reported Outcomes in Phase 3 Study Analyses

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INDIANAPOLIS, April 23, 2021 /PRNewswire/ Through new analyses of BREEZE-AD5 Phase 3 clinical trial data and an extended safety analysis across multiple trials, Eli Lilly and Company (NYSE: LLY) and Incyte s (NASDAQ:INCY) OLUMIANT
® (baricitinib) 2-mg tablet taken once daily showed improvement in key measured treatment outcomes compared to placebo, and helped further characterize the long-term safety profile in adults with moderate to severe atopic dermatitis (AD). In one BREEZE-AD5 analysis, OLUMIANT provided concurrent improvements in the severity and extent of AD, other key symptoms and quality of life as early as one week, as measured by percent change from baseline compared to placebo. In a separate BREEZE-AD5 analysis, adults with AD on 10-50% of their bodies at baseline who were treated with OLUMIANT showed significant improvements in the severity and extent of disease compared to placebo. In the integrated safety a ....

United States , Catalina Loveman , Kevin Hern , Eric Simpson , Christine Chiou , Marlo Scott , Eli Lilly , Exchange Commission , American Academy Of Dermatology Virtual Meeting Experience , European Union , Drug Administration , American Academy , Virtual Meeting Experience , Lotus Mallbris , Concurrently Improved Extent , Key Symptoms , Their Bodies , Baseline Treated , Experienced Significant Improvements , Body Surface Area , Eczema Area Severity Index , Investigator Global Assessment , Atopic Dermatitis , Clinical Research , Oregon Health , Science University ,

Sun Pharma to Present Clinical Data Abstracts for ILUMYA® (tildrakizumab-asmn) in Patients with Moderate-to-Severe Plaque Psoriasis at the AAD Virtual Meeting Experience 2021

Sun Pharma to Present Clinical Data Abstracts for ILUMYA® (tildrakizumab-asmn) in Patients with Moderate-to-Severe Plaque Psoriasis at the AAD Virtual Meeting Experience 2021
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Sun Pharma to Present Clinical Data Abstracts for ILUMYA® (tildrakizumab-asmn) in Patients with Moderate-to-Severe Plaque Psoriasis at the AAD Virtual Meeting Experience 2021

Sun Pharma to Present Clinical Data Abstracts for ILUMYA® (tildrakizumab-asmn) in Patients with Moderate-to-Severe Plaque Psoriasis at the AAD Virtual Meeting Experience 2021
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United States , Sun Pharma , States Sun Pharma , Abhay Gandhi , Gaurav Chugh , American Academy Of Dermatology Virtual Meeting Experience , Sun Pharmaceutical Industries Limited , Sun Pharmaceutical Industries Ltd , Sun Pharmaceutical Industries Inc , American Academy , Dermatology Virtual Meeting Experience , Meeting Experience , Sun Pharmaceutical Industries , Pharmaceutical Industries Ltd , ஒன்றுபட்டது மாநிலங்களில் , சூரியன் பார்மா , கௌராவ் சக் , அமெரிக்கன் கலைக்கழகம் ஆஃப் தோல் நோய் மெய்நிகர் சந்தித்தல் அனுபவம் , சூரியன் மருந்து தொழில்கள் வரையறுக்கப்பட்டவை , சூரியன் மருந்து தொழில்கள் லிமிடெட் , சூரியன் மருந்து தொழில்கள் இன்க் , அமெரிக்கன் கலைக்கழகம் , தோல் நோய் மெய்நிகர் சந்தித்தல் அனுபவம் , சந்தித்தல் அனுபவம் , சூரியன் மருந்து தொழில்கள் , மருந்து தொழில்கள் லிமிடெட் ,