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Stroke occurs infrequently in large cohort study of patients hospitalized with COVID-19

Stroke occurs infrequently in large cohort study of patients hospitalized with COVID-19
Source:
Fanning J, et al. Stroke complicating critically ill patients with SARS-CoV-2: Analysis of the COVID-19 Critical Care Consortium (CCCC) international, multicenter observational study. Presented at: American Academy of Neurology Annual Meeting; April 17-22, 2021 (virtual meeting).
Disclosures:
Healio Neurology could not confirm relevant financial disclosures at the time of publication.
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Mayo study differentiates what blood-based proteins indicate about brain cell loss

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Mayo study differentiates what blood-based proteins indicate about brain cell loss
Two proteins that can be measured in the blood – plasma total tau and neurofilament light – are associated with brain cell loss that causes memory and thinking problems. Neurofilament light was more strongly related to worse cognition and neurodegeneration, compared to total tau, according to a preliminary Mayo Clinic study that will be presented in the Emerging Science program at the 2021 virtual American Academy of Neurology Annual Meeting.
Brain cell loss, or neurodegeneration, is a common characteristic of many disorders, including Alzheimer’s disease, vascular dementia and Lewy body dementia. However, the causes and location of neurodegeneration in the brain vary depending on the disease. ....

United States , Jeremy Syrjanen , Prashanthi Vemuri , Micheller Campbell , Alicia Algeciras Schimnich , Ronald Petersen , Michelle Mielke , Mary Machulda , Clifford Jack Jr , Jonathan Graff Radford , David Knopman , Alzheimer Disease Neuroimaging Initiative , American Academy Of Neurology Annual Meeting , National Institutes Of Health , National Institute On , Mayo Clinic , Emerging Science , American Academy , Neurology Annual , Mayo Clinic Study , Disease Neuroimaging Initiative , Jordan Marks , National Institutes , National Institute , Rochester Epidemiology , Public Release ,

Study: Black People May Respond Differently to Common MS Therapy than White People

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MINNEAPOLIS, April 16, 2021 /PRNewswire/ A preliminary study suggests that Black people who have autoimmune neurologic diseases, multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD), may respond differently than white people to a common therapy meant to modulate the immune system. The research will be presented at the American Academy of Neurology s 73rd Annual Meeting being held virtually April 17 to 22, 2021.
The people in this study were given anti-CD20 infusion therapies, which are often used to treat autoimmune diseases such as MS and neuromyelitis optica spectrum disorder, which is a relapsing inflammatory disorder of the optic nerve, spinal cord and brain. The goal of this treatment, called B-cell depletion therapy, is to destroy B-cells in blood circulation. B-cells are partly responsible for the abnormal autoimmune responses in people with MS and NMOSD. ....

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Study: Black People May Respond Differently to Common MS Therapy than White People

Study: Black People May Respond Differently to Common MS Therapy than White People
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How common is stroke in people critically ill with COVID-19?

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MINNEAPOLIS - A large, year-long study has found that among people with COVID-19 who were hospitalized in an intensive care unit (ICU), 2% experienced a stroke after they were admitted to the ICU. The preliminary study released today, April 15, 2021, will be presented at the American Academy of Neurology s 73rd Annual Meeting being held virtually April 17 to 22, 2021. The study also found that hemorrhagic stroke, a bleeding stroke, was associated with a higher risk of death among people in the ICU, but ischemic stroke, a stroke caused by a blood clot blocking an artery, was not.
Stroke has been a known serious complication of COVID-19 with some studies reporting a higher-than-expected occurrence, especially in young people, said study author Jonathon Fanning, M.B.B.S., Ph.D., of the University of Queensland in Brisbane, Australia, and a member of the American Academy of Neurology. However, among the sickest of patients, those admitted to an ICU, our research fo ....

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