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Cells create own detergent to clean up infections


By Bill Hathaway
July 15, 2021
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(Illustration by Michael S. Helfenbein)
In recent years, scientists have discovered that non-immune system cells are surprisingly well armed to combat infection. Yale researchers have found a particularly powerful weapon in these cells’ arsenal a protein that acts like a detergent to wipe out invading pathogens much like the way that Ajax cleans dirty dishes or sanitizes a kitchen countertop.
This intracellular cleanser, the researchers say, dissolves membranes of invading bacteria that have replicated in the cytosol, the watery interior of cells. Importantly, the detergent-like immune protein does not harm the membranes of organelles belonging to the host cell, they report July 16 in the journal Science. ....

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Redirecting to Yale-Boehringer Ingelheim Biomedical Data Science Fellowship Program Seeks to Attract Top Researchers from Around the World


Yale-Boehringer Ingelheim Biomedical Data Science Fellowship Program Seeks to Attract Top Researchers from Around the World
Yale University, in partnership with Boehringer Ingelheim, today announced the launch of a Biomedical Data Science Fellowship program designed to attract and support some of the brightest and most innovative minds in data science from around the world.
Post-doctoral researchers awarded a three-year fellowship will have access to Yale’s robust computational resources, biomedical data repositories and faculty expertise. In addition, they will benefit from access to Boehringer Ingelheim’s corporate labs, scientists and executives. Applicants are invited to submit research proposals for consideration by June 15. If approved for a fellowship, they will be jointly mentored throughout the research process by industry experts and scientists from Boehringer Ingelheim one of the world’s leading pharmaceutical companies as well as Yale’s world-class ....

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