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Key to Limiting Mucus Production in Lung Disease Identified

Key to Limiting Mucus Production in Lung Disease Identified
genengnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from genengnews.com Daily Mail and Mail on Sunday newspapers.

Bob Xaralabos Varelas , Yap Taz , Research Scholar Grant , Researchers At Boston University , Breast Cancer Foundation , National Institutes Of Health , Janssen Pharmaceuticals , Boston University , Boston University School Of Medicine , Boston University School , Cell Reports , National Institutes , Scholar Grant , Cause Breast Cancer Foundation , Moorman Simon Fellowships , யாப் தாஜ் , ஆராய்ச்சி அறிஞர் மானியம் , ஆராய்ச்சியாளர்கள் இல் போஸ்டன் பல்கலைக்கழகம் , மார்பக புற்றுநோய் அடித்தளம் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , ஜான்சன் மருந்துகள் , போஸ்டன் பல்கலைக்கழகம் , போஸ்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , போஸ்டன் பல்கலைக்கழகம் பள்ளி , செல் அறிக்கைகள் , தேசிய நிறுவனங்கள் ,

New research identifies key set of signals that control mucus production in the lung

New research identifies key set of signals that control mucus production in the lung
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

United States , Boston University , Bob Xaralabos Varelas , Yap Taz , Research Scholar Grant , Breast Cancer Foundation , Boston University Sequencing Core , Janssen Pharmaceuticals Sponsored Research Agreement , Boston University School Of Medicine , Boston University School , Cystic Fibrosis , Flow Cytometry Core , Scholar Grant , Cause Breast Cancer , Moorman Simon Fellowships , Janssen Pharmaceuticals Sponsored Research , ஒன்றுபட்டது மாநிலங்களில் , போஸ்டன் பல்கலைக்கழகம் , யாப் தாஜ் , ஆராய்ச்சி அறிஞர் மானியம் , மார்பக புற்றுநோய் அடித்தளம் , போஸ்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , போஸ்டன் பல்கலைக்கழகம் பள்ளி , சிஸ்டிக் ஃபைப்ரோஸிஸ் , ஓட்டம் சைட்டோமெட்ரி கோர் , அறிஞர் மானியம் ,

KidneyCure announces 2021 grant recipients

KidneyCure announces 2021 grant recipients
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

United States , Northwestern University , Tufts Medical Center , Tanecia Mitchell , Dan Wang , Enrico Cocchi , Carolinem Hsu , Riana Parvez , Suzanne Boyle , Ronak Lakhia , Irma Husain , Felix Poppelaars , John Yongjoon Choi , Sarahn Lipp , Elinor Mannon , Fabian Bock , Amandaj Clark , Konstantin Deutsch , Yanhua Wang , Meredith Posner Schuh , Evanc Ray , Mary Hannan , Eirini Kefalogianni , Jennie Lin , Ghazalz Quinn , Eugene Lin ,

Intratumoral SIRPalpha-deficient macrophages activate tumor-specific cytotoxic T cells

In a study that will be published in Nature Communications on May 28, 2021, a research team led by Dr. Yuan Liu from Georgia State University reports that intratumoral SIRPalpha-deficient macrophages activate tumor antigen-specific cytotoxic T cells to eliminate various syngeneic cancers under radiotherapy. Their study identifies SIRPalpha as a master regulator controling macrophage immune responses and has demonstrated that intratumoral injection of SIRPalpha-depleted macrophages combined with local radiation is an effective strategy to treat different tumors ....

United States , Georgia State University , Ahmedt Abdelaal , Koby Kidder , Charlie Garnett Benson , Venture Development , National Institutes Of Health , Program Of Cancer , Nature Communications On , Research Scholar Grant , American Association Of Immunologist , American Cancer Society , Georgia Research Alliance , Nature Communications , Yuan Liu , Zhen Bian , Lei Shi , National Institutes , Biolocity Innovation , American Association , Molecular Basis , Molecular Genetics , Medicine Health , ஒன்றுபட்டது மாநிலங்களில் , ஜார்ஜியா நிலை பல்கலைக்கழகம் , துணிகர வளர்ச்சி ,

Fundamental mechanism discovered that fine-tunes gene expression & is disrupted in cancer

Credit: The Wistar Institute
PHILADELPHIA and MELBOURNE, Australia (May. 17, 2021) A team of scientists from The Wistar Institute in Philadelphia and the Peter MacCallum Cancer Center in Melbourne, Australia, discovered a new checkpoint mechanism that fine-tunes gene transcription. As reported in a study published in
Cell, a component of the Integrator protein complex tethers the protein phosphatase 2A (PP2A) to the site of transcription allowing it to stop the activity of the RNA polymerase II enzyme (RNAPII). Disruption of this mechanism leads to unrestricted gene transcription and is implicated in cancer.
The study points to new viable opportunities for therapeutic intervention demonstrating the anti-cancer effect of a new combination treatment in preclinical models of solid and hematopoietic malignancies. ....

New York , United States , Dana Farber Cancer Institute , New South Wales , Benjamin Blyth , Otto Kauko , Jenniferr Devlin , Saraha Welsh , Elisa Barbieri , Kaylenej Simpson , Edwind Hawkins , Michael Ohlmeyer , Deboraha Knight , Matteo Costacurta , Stefan Bjelosevic , Gareth Gregory , Simonj Hogg , Ricky Johnstone , Elena Demosthenous , Magnus Zethoven , Jarrodj Sandow , Benp Martin , Conorj Kearney , Izabela Todorovski , Joseph Ha Vissers , Madisonj Kelly ,