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Prognostic Marker Identified for Invasive Bladder Cancer


Prognostic Marker Identified for Invasive Bladder Cancer
by Angela Mohan on 
June 1, 2021 at 12:56 PM
In the new study 32 patients developed recurrent disease and 15 patients showed progression.
A multivariate analysis revealed that non-BCG treatment was an independent risk factor for recurrence, and a higher De Ritis ratio was an independent risk factor for cancer progression.
Dr. Takashi Kawahara from The Yokohama City University Medical Center said, Bladder cancer is the eleventh most common malignant disease in the world, and non-muscle invasive bladder cancer (NMIBC) accounts for 75% of all bladder cancer cases.
The serum aspartate aminotransaminase /alanine aminotransaminase ratio was first reported by De Ritis in 1957, since then this ratio has been called the De Ritis ratio. ....

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COVID Shot Shows Less Efficacy in Few Blood Cancer Patients


COVID Shot Shows Less Efficacy in Few Blood Cancer Patients
by Angela Mohan on 
April 19, 2021 at 12:10 PM
Blood.
The findings suggest that the mRNA COVID-19 vaccine may have reduced efficacy in people with chronic lymphocytic leukemia (CLL) and multiple myeloma, two types of blood cancer compared to healthy people.
However, vaccination against COVID-19 is strongly recommended in both groups, the researchers said.
Even though response rates were not optimal, patients with CLL should still get the vaccine and, if appropriate, it may be better to do so before CLL treatment starts although the disease itself may affect the response, said lead author Yair Herishanu, Associate Professor in hematology and head of the CLL service at the Tel Aviv Sourasky Medical Centre in Israel. ....

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