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Study identifies new targets in the angiogenesis process

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IMAGE: Blocking the Orai1- and SARAF-dependent calcium pathway affects retinal vessel formation, the development of new vessels from aortic rings, as well as the proliferation, migration and tube arrangement of endothelial.
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Credit: Universidad de Sevilla
Angiogenesis is a process of new vessel formation that is activated both in physiological (tissue repair, reproduction, etc.) and pathological (myocardial infarction, diabetic retinopathy, cancer, etc.) conditions. The process is carried out by endothelial cells and includes their proliferation, migration and arrangement in tubes. Angiogenesis regulation is precise and is mainly mediated by pro-angiogenic factors, such as vascular endothelial growth factor (VEGF), which in turn promote different signalling pathways leading to an increase of intracellular Ca2+ concentrations. ....

University Of Bordeaux , Research Agency , University Of Extremadura , Institute Of Biomedicine Seville Ibi , Cardiovascular Pathophysiology , Agencia Estatal De Investigaci , State Research Agency , Medicine Health , பல்கலைக்கழகம் ஆஃப் போர்டியாக்ஸ் , இருதய நோயியல் இயற்பியல் ,

Researchers identify new targets to control angiogenesis

Researchers identify new targets to control angiogenesis
Angiogenesis is a process of new vessel formation that is activated both in physiological (tissue repair, reproduction, etc.) and pathological (myocardial infarction, diabetic retinopathy, cancer, etc.) conditions.
The process is carried out by endothelial cells and includes their proliferation, migration and arrangement in tubes. Angiogenesis regulation is precise and is mainly mediated by pro-angiogenic factors, such as vascular endothelial growth factor (VEGF), which in turn promote different signaling pathways leading to an increase of intracellular Ca2+ concentrations.
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The researchers from the Cardiovascular Pathophysiology group at the Institute of Biomedicine of Seville (IBiS) focused on precisely this point, demonstrating that the inhibition of certain proteins involved in the pathway s regulation drastically affects the proper development of blood vessels. ....

Emily Henderson , Institute Of Biomedicine Seville Ibi , Cardiovascular Pathophysiology , எமிலி ஹென்டர்சன் , இருதய நோயியல் இயற்பியல் ,

Re: Red meat intake and risk of coronary heart disease among US men: prospective cohort study

Re: Red meat intake and risk of coronary heart disease among US men: prospective cohort study
bmj.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from bmj.com Daily Mail and Mail on Sunday newspapers.

United States , Idaho College Of Osteopathic Medicine , Blood Viscosity Its Role , Cardiovascular Pathophysiology , Arch Cardiovasc Dis , ஒன்றுபட்டது மாநிலங்களில் , ஐடஹோ கல்லூரி ஆஃப் ஒஸ்திேோப்பததிக் மருந்து , இருதய நோயியல் இயற்பியல் ,