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Study sheds new light on complex dynamics involved in microbial infections

Study sheds new light on complex dynamics involved in microbial infections
Included in the vast fallout stemming from the COVID-19 pandemic, scientists are paying closer attention to microbial infections and how life forms defend against attacks from pathogens.
Research led by University of California San Diego scientists has shed new light on the complex dynamics involved in how organisms sense that an infection is taking place.
UC San Diego Assistant Project Scientist Eillen Tecle in Professor Emily Troemel s laboratory (Division of Biological Sciences) led research focusing on how cells that are not part of the conventional immune system respond to infections when pathogens attack. Scientists have conducted extensive research on so-called professional immune cells that are defensive specialists. Much less is known about how non-professional cells handle such threats. ....

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New tumor-penetrating therapy may improve outcomes in patients with pancreatic cancer

New tumor-penetrating therapy may improve outcomes in patients with pancreatic cancer
Every 12 minutes, someone in the United States dies of pancreatic cancer, which is often diagnosed late, spreads rapidly and has a five-year survival rate at approximately 10 percent. Treatment may involve radiation, surgery and chemotherapy, though often the cancer becomes resistant to drugs.
Researchers at University of California San Diego School of Medicine and Moores Cancer Center, in collaboration with Sanford-Burnham-Prebys Medical Discovery Institute and Columbia University, demonstrated that a new tumor-penetrating therapy, tested in animal models, may enhance the effects of chemotherapy, reduce metastasis and increase survival.
The study, published online March 9, 2021 in ....

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Climate change and suppression tactics are critical factors increasing fires

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IMAGE: A recent study shows that in some ecosystems, human-caused climate change is the predominant factor for wildfires; in other places, the trend can also be attributed to a century of.
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Credit: Photo Courtesy University of Nevada, Reno
The millions of people affected by 2020 s record-breaking and deadly fires can attest to the fact that wildfire hazards are increasing across western North America.
Both climate change and forest management have been blamed, but the relative influence of these drivers is still heavily debated. The results of a recent study show that in some ecosystems, human-caused climate change is the predominant factor; in other places, the trend can also be attributed to a century of fire suppression that has produced dense, unhealthy forests. ....

United States , Sierra Nevada , Johnt Abatzoglou , Christinal Tague , Mingliang Liu , Maureenc Kennedy , Erin Hanan , Santa Barbara , Erinj Hanan , Ryanr Bart , Jenniferc Adam , Naomi Tague , Jianning Ren , Washington State University , University Of California , Research Professor , Authors Of The Environmental Research Letters , Sierra Nevada Research Institute , College Of Agriculture , National Science , Department Of Civil Environmental Engineering , Environmental Research Letters , School Of Interdisciplinary Arts Sciences , University Of Washington , University Of Nevada , Gallo Management Program ,