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Landscape study launched to detect liver cancer early in Singapore

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IMAGE: Quantitative MR images of the liver from six patients presenting with liver cancer produced by Perspectum s LiverMultiScan which will be used in a new study led by National Cancer Centre.
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Credit: Mole DJ et al. Plos One. 2020;15(12):e0238568
Singapore, 3 May 2021 - A first of its kind cohort study on patients at high risk of developing primary liver cancer also known as hepatocellular carcinoma (HCC), has been launched to diagnose HCC more accurately at an earlier stage and to predict an individual s likelihood of developing the cancer. HCC is the sixth most common cancer in the world but the third most common cause of cancer deaths globally.[1] In Singapore, HCC is the third and fourth most common cause of cancer deaths, amongst males and females respectively.[2] While potentially curative treatment is possible with early diagnosis, only 20% of HCC cases are detected at a stage where cure is possible. This investigator-initiated ....

National University Hospital , Singapore General , Marine Parade , Tan Tock Seng Hospital , Bukit Merah , Mihir Gandhi , Asia Pacific , Wang Yulan , Dan Yock Young , Jason Chang Pik , Centre For Quantitative Medicine , National Registry Of Diseases Office , Division Of Gastroenterology , Agency Of Science , Lee Kong Chian School Of Medicine , National Cancer Centre Of Singapore , Nanyang Technological University Singapore , Singapore Phenome Centre , Department Of Gastroenterology Hepatology , National Cancer Centre Singapore , Division Of Surgery , Health Services Systems Research Signature Programme , National Cancer Centre , Prof Pierce Chow , Principal Investigator , Senior Consultant ,

LANDMARK STUDY LAUNCHED TO DETECT LIVER CANCER EARLY IN SINGAPORE

LANDMARK STUDY LAUNCHED TO DETECT LIVER CANCER EARLY IN SINGAPORE
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National University Hospital , Singapore General , Marine Parade , Tan Tock Seng Hospital , Bukit Merah , Mihir Gandhi , Asia Pacific , Wang Yulan , Dan Yock Young , Jason Chang Pik , Centre For Quantitative Medicine , Division Of Gastroenterology , Agency Of Science , Lee Kong Chian School Of Medicine , National Cancer Centre Of Singapore , Nanyang Technological University Singapore , Singapore Phenome Centre , Department Of Gastroenterology Hepatology , National Cancer Centre Singapore , Division Of Surgery , Health Services Systems Research Signature Programme , National Cancer Centre , Prof Pierce Chow , Principal Investigator , Senior Consultant , Surgical Oncology ,

Study explores how environmental exposures before conception may impact fetal development

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GRAND RAPIDS, Mich. (March 16, 2021) Older age at the time of conception and alcohol consumption during pregnancy have long been known to impact fetal development.
Proceedings of the National Academy of Sciences suggests older age and alcohol consumption in the year leading up to conception also may have an impact by epigenetically altering a specific gene during development of human eggs, or oocytes.
Although the study did not determine the ultimate physical effects of this change, it provides important insights into the intricate relationship between environmental exposures, genetic regulation and human development.
While the outcome of the change isn t clear, our findings give us a valuable look into how environmental factors affect gene regulation through epigenetics and imprinting, said Peter A. Jones, Ph.D., D.Sc. (hon), Van Andel Institute chief scientific officer and the study s senior author. A better understanding of these complex processe ....

South Africa , Western Cape , Tanakak Remba , Staceyl Thomas , Zachary Madaj , Rochellel Tiedemann , Heinj Odendaal , Petera Jones , Human Development , National Institutes Of Health , National Institute On Deafness , National Institute On Alcohol Abuse , Stillbirth Network , Proceedings Of The National Academy Sciences , Stellenbosch University , National Institute , Van Andel Institute , National Academy , Biostatistics Core , Prenatal Alcohol , General Medical Sciences , National Institutes , Safe Passage Study , Alcohol Abuse , Eunice Kennedy Shriver National Institute , Child Health ,

Firma Clinical Commences Scientific Advisory Board

Firma Clinical Commences Scientific Advisory Board
Board Includes Experts from Harvard, Stanford, UConn and a former FDA Director
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CHICAGO, March 10, 2021 /PRNewswire/ Firma Clinical, a niche service provider to clinical research organizations, recently commenced a Scientific Advisory Board for its clinical services, including biometrics/data. The board includes scientific experts from Harvard University, Stanford University and the University of Connecticut and the FDA s former Director of the Division of Biostatistics. The board members provide
Firma with strategic advice and education and are resources for the latest statistical methodology and regulatory requirements. ....

United States , Soochow University , T Ai Pei , Ying Lu , Palo Alto , Stanford University , Dana Farber Cancer Institute , Harvard University , Harvard School Of Public Health , Patty Pologruto , Eugenia Henry , Earl Webb Henry , Ming Hui Chen , Greg Campbell , Michael Woods , Dejun Tang , University Of Michigan , Society For Clinical Trials Dr , George Washington University , Radiological Health , American Association For The Advancement Of Science , Drug Administration Center , Longwood Neurology Program , Head Of Clinical Research , Population Health , Inventiv Health ,