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Molecular dynamic analysis of SARS-CoV-2 inhibitors


Molecular dynamic analysis of SARS-CoV-2 inhibitors
As of July 13, 2021, the coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected over 187 million people and caused the deaths of over 4 million people worldwide. Upon infection by SARS-CoV-2, this virus binds with high affinity to the human angiotensin converting enzyme-2 (ACE2) receptor present on the surface of human cells. This mechanism has therefore been of interest to many researchers looking to develop treatments that could block ACE2 and/or disable the spike (S) protein of SARS-CoV-2.
A new study reports the results of molecular dynamic simulations that were performed in an effort to identify new drugs that could be effective against SARS-CoV-2. ....

Michal Bednarek Shutterstock , Biomolecular Structure , உயிர் மூலக்கூறு அமைப்பு ,

A closer look at how COVID-19 damages human lungs


A closer look at how COVID-19 damages human lungs
A recent study conducted at the United States Department of Energy’s (DOE) Brookhaven National Laboratory provides the first atomic-level detailed model of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope protein when bound to human proteins within the lungs. The study was recently published in
The utility of cryo-EM
Cryo-electron microscopy (cryo-EM) is a high-resolution imaging technology that uses frozen samples, gentle electron beams, and sophisticated imaging software to acquire highly detailed images. The electrons used in cryo-EM, as well as other forms of EM, allow scientists to visualize biological molecules at a much smaller scale as a result of their extremely short wavelength. In fact, it is estimated that the wavelength of electrons is 100,000 times shorter than that of visible light. ....

United States , Liguo Wang , Nature Communications , United States Department Of Energy , Brookhaven Lab Laboratory For Biomolecular Structure , Brookhaven National Laboratory , United States Department , Brookhaven Lab , Biomolecular Structure , Coronavirus Disease Covid 19 , Ars Cov 2 , Electron Microscopy , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , ஒன்றுபட்டது மாநிலங்களில் , இயற்கை தகவல்தொடர்புகள் , ஒன்றுபட்டது மாநிலங்களில் துறை ஆஃப் ஆற்றல் , ப்ரூக்ஹவன் ஆய்வகம் ஆய்வகம் க்கு உயிர் மூலக்கூறு அமைப்பு , ப்ரூக்ஹவன் தேசிய ஆய்வகம் , ஒன்றுபட்டது மாநிலங்களில் துறை , ப்ரூக்ஹவன் ஆய்வகம் , உயிர் மூலக்கூறு அமைப்பு ,

A novel multi-epitope COVID-19 vaccine developed using reverse vaccinology


A novel multi-epitope COVID-19 vaccine developed using reverse vaccinology
In late December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, and subsequently spread rapidly across the world. On the 11th of March 2020, the World Health Organization announced the global outbreak of coronavirus disease 2019 (COVID-19) as a pandemic. Scientists around the world are working extensively to develop new vaccines, therapeutics, and many other strategies to contain the pandemic.
SARS-CoV-2 is a positive-sense and single-stranded RNA virus that belongs to the genus Betacoronavirus of the Coronaviridae family. Some of the members of this family affect humans by causing common cold (HCoV-229E, HCoV-NL63, and HCoV-OC43), SARS (Severe Acute Respiratory Syndrome), and MERS (Middle East Respiratory Syndrome). ....

Priyom Bose , World Health Organization , Severe Acute Respiratory Syndrome , Middle East Respiratory Syndrome , Biomolecular Structure , Toll Like Receptors , Root Mean Square Fluctuation , Common Cold , Coronavirus Disease Covid 19 , Immune System , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome , T Cell , பிரீயோம் போஸ் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி , நடுத்தர கிழக்கு சுவாச நோய்க்குறி , உயிர் மூலக்கூறு அமைப்பு , டி செல் ,

UM Student Earns Top Score on MCAT Exam


UM Student Earns Top Score on MCAT Exam
University of Montana
19 March 2021
UM student Devin Hunt earned a top score on the Medical College Admission Test. The biology and microbiology major was awarded a yearlong fellowship next year with the National Institute of Allergy and Infectious Diseases.
MISSOULA – Devin Hunt said he technically cracked the first book to prepare for the Medical College Admission Test, or MCAT, in August. But the truth, Hunt said, is that spending four years at the University of Montana deeply embedded in microbiology and biology classes, working in research labs and studying under the tutelage of faculty mentors, meant he had really been preparing for years. ....

National Institutes Of Health , United States , Patrick Secor , Dave Kuntz , Mark Pershouse , Um Department Of Biomedical , National Institute Of Allergy , University Of Montana , Um Division Of Biological Sciences , College Admission Test , Yum Center , Secor Bacteriophage Pathobiology Lab , Postbaccalaureate Intermural Research Training , Association Of American Medical Colleges , Princeton Review , Um Davidson Honors College , Devin Hunt , Medical College Admission Test , Honors College , American Medical Colleges , Regents Professor , Evolutionary Biology Doug Emlen , Biological Sciences , Associate Professor Mark Pershouse , Pharmaceutical Sciences , Assistant Professor Patrick Secor ,