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Shanghai Genechem Co., Ltd. (Genechem) Announces appointment of Dr. Eric Rowinsky and Dr. Manuel Hidalgo to Scientific Advisory board, and abstract presentation at AACR 2021 on Claudin 6 Ab and K-Ras TCR-T


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SHANGHAI, April 8, 2021 /PRNewswire/ Shanghai Genechem Co., Ltd. (Genechem), a discovery company dedicated to novel target discovery and development of novel therapeutics, today announced the appointment of Dr. Eric Rowinsky, President and Executive Chairman of the Board of Rgenix, Inc., and Dr. Manuel Hidalgo, Chief of Hematology and Medical Oncology at Weill Cornell Medicine and NewYork-Presbyterian/Weill Cornell Medical Center, to its Scientific Advisory Board. Drs. Rowinsky and Hidalgo will bring their strong expertise in translational and clinical development to support Genechem s mission to bring its innovative pipeline to global markets through novel target discovery, early development in China, and global partnership. ....

United States , San Antonio , University Of Texas , Eric Rowinsky , Manuel Hidalgo , Hughe Luckey , Yueqiong Cao , Johns Hopkins University , Head Of Research , Beth Israel Deaconess Medical Center , Presbyterian Weill Cornell Medical Center , Clearpath Development Co , Institute Of Drug Development , University Autonoma , Early Drug Development , Purple Biotech Ltd , Johns Hopkins School Of Medicine , Prnewswire Shanghai Genechem Co Ltd , Clinical Research , Gastrointestinal Oncology Program , Stemline Therapeutics Inc , Translational Research , Division Of Hematology , Kimmel Comprehensive Cancer Center At Johns Hopkins , Clinical Research Program , Good Research Practice ,

Cancer cells may evade chemotherapy by going dormant


March 16, 2021
Cancer cells can dodge chemotherapy by entering a state that bears similarity to certain kinds of senescence, a type of “active hibernation” that enables them to weather the stress induced by aggressive treatments aimed at destroying them, according to a new study by scientists at Weill Cornell Medicine.
These findings have implications for developing new drug combinations that could block senescence and make chemotherapy more effective.
In a study published Jan. 26 in Cancer Discovery, a journal of the American Association for Cancer Research, the investigators reported that this biologic process could help explain why cancers so often recur after treatment. The research was done in both organoids and mouse models made from patients’ samples of acute myeloid leukemia (AML) tumors. The findings were also verified by looking at samples from AML patients that were collected throughout the course of treatment and relapse.  ....

Fox Chase Cancer Center , United States , Cihangir Duy , American Association For Cancer Research , Edward Meyer Cancer Center , Weill Cornell , Cancer Discovery , American Association , Cancer Research , Gebroe Family Professor , Medical Oncology , நரி துரத்து புற்றுநோய் மையம் , ஒன்றுபட்டது மாநிலங்களில் , அமெரிக்கன் சங்கம் க்கு புற்றுநோய் ஆராய்ச்சி , எட்வர்ட் மேயர் புற்றுநோய் மையம் , வெயில் கார்னெல் , புற்றுநோய் கண்டுபிடிப்பு , அமெரிக்கன் சங்கம் , புற்றுநோய் ஆராய்ச்சி , மருத்துவ புற்றுநோயியல் ,

Cancer cells may dodge chemotherapy by going into 'active hibernation'


Cancer cells may dodge chemotherapy by going into active hibernation
Cancer cells can dodge chemotherapy by entering a state that bears similarity to certain kinds of senescence, a type of active hibernation that enables them to weather the stress induced by aggressive treatments aimed at destroying them, according to a new study by scientists at Weill Cornell Medicine. These findings have implications for developing new drug combinations that could block senescence and make chemotherapy more effective.
In a study published Jan. 26 in
Cancer Discovery, a journal of the American Association for Cancer Research, the investigators reported that this biologic process could help explain why cancers so often recur after treatment. The research was done in both organoids and mouse models made from patients samples of acute myeloid leukemia (AML) tumors. The findings were also verified by looking at samples from AML patients that were collected throughout the course of t ....

United States , Fox Chase Cancer Center , Cihangir Duy , Emily Henderson , American Association For Cancer Research , Constellation Pharmaceuticals , Weill Cornell , Cancer Discovery , American Association , Cancer Research , Gebroe Family Professor , Medical Oncology , Edward Meyer Cancer Center , Ari Melnick , Acute Myeloid Leukemia , Myeloid Leukemia , ஒன்றுபட்டது மாநிலங்களில் , நரி துரத்து புற்றுநோய் மையம் , எமிலி ஹென்டர்சன் , அமெரிக்கன் சங்கம் க்கு புற்றுநோய் ஆராய்ச்சி , விண்மீன் மருந்துகள் , வெயில் கார்னெல் , புற்றுநோய் கண்டுபிடிப்பு , அமெரிக்கன் சங்கம் , புற்றுநோய் ஆராய்ச்சி , மருத்துவ புற்றுநோயியல் ,