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New Guidelines for Hematopoietic Stem Cell Transplantation for MS


iStock
Hematopoietic stem cell transplantation (HSCT) or, more correctly autologous hematopoietic stem cell transplantation (AHSCT) has long been a horizon-dwelling promise for people living with multiple sclerosis (MS).
For those to whom AHSCT is not a familiar term, bone marrow transplant is often the lay term used for the procedure.
The therapy was first put to use for people with particular types of cancer with mixed effect. The transition from cancer therapy to MS treatment was a rocky one, during which many lives were put at risk and some were lost.
Full disclosure: I personally knew two people who died during their participation in AHSCT trials. Their sacrifice helped lead researchers and patient advocates to modify and improve the treatment to the point it can now be recommended to some people living with MS. ....

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Redirecting to Takeda FY2020 Q3 Results Demonstrate Growth Acceleration and Continued Resilience; Full-Year Management Guidance for FY2020 Confirmed, Forecast Raised for Free Cash Flow and Reported EPS


717.5
-3.8%
(1) Further information on certain of Takeda’s Non-IFRS measures is posted on Takeda’s investor relations website at https://www.takeda.com/investors/reports/quarterly-announcements/
(2) Underlying growth compares two periods (quarters or years) of financial results under a common basis and is used by management to assess the business. These financial results are calculated on a constant currency basis and excluding the impact of divestitures and other amounts that are unusual, non-recurring items or unrelated to our ongoing operations.
(3) Core Operating Profit represents net profit adjusted to exclude income tax expenses, the share of profit or loss of investments accounted for using the equity method, finance expenses and income, other operating expenses and income, amortization and impairment losses on acquired intangible assets and other items unrelated to Takeda’s core operations, such as purchase accounting effects and transaction relate ....

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Takeda FY2020 Q3 Results Demonstrate Growth Acceleration and Continued Resilience Full-Year Management Guidance for FY2020 Confirmed, Forecast Raised for Free Cash Flow and Reported EPS


(1)
Further information on certain of Takeda’s Non-IFRS measures is posted on Takeda’s investor relations website at
(2)
Underlying growth compares two periods (quarters or years) of financial results under a common basis and is used by management to assess the business. These financial results are calculated on a constant currency basis and excluding the impact of divestitures and other amounts that are unusual, non-recurring items or unrelated to our ongoing operations.
(3)
Core Operating Profit represents net profit adjusted to exclude income tax expenses, the share of profit or loss of investments accounted for using the equity method, finance expenses and income, other operating expenses and income, amortization and impairment losses on acquired intangible assets and other items unrelated to Takeda’s core operations, such as purchase accounting effects and transaction related costs. ....

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