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Scientists report 6 novel variants in CRISPR-Cas12a in plants, expanding genome engineering

Discovery offers patentable tools to improve the efficiency of food production
Scientists are expanding genome editing and engineering in plants
April 8, 2021
The research of plant scientist Yiping Qi at the University of Maryland focuses on innovative genome editing and engineering techniques in plants, with the goal of improving the efficiency of food production.
Nature Communications by Qi and colleagues, contribute six novel variants of CRISPR-Cas12a that have never before been proven in plants, testing them first in rice, a major global crop.
In addition to allowing for a much broader scope of possible gene editing targets, these new tools can edit many different sites in the genome at once, or repress gene expression to tone down undesirable traits. These patent-pending tools greatly expand the scope of what CRISPR-Cas12a can do in plants, which can help produce food more effectively to feed a growing global population. ....

Yiping Qi , Diane Okamuro , Division Of Integrative Organismal Systems , Nature Communications , Research News , University Of Maryland , Nsfpublic Affairs , Us National Science , Science Foundation Funded , Integrative Organismal Systems , பிரிவு ஆஃப் ஒருங்கிணைந்த ஒர்கனிஸ்மால் அமைப்புகள் , இயற்கை தகவல்தொடர்புகள் , ஆராய்ச்சி செய்தி , பல்கலைக்கழகம் ஆஃப் மேரிலாந்து , எங்களுக்கு தேசிய அறிவியல் , அறிவியல் அடித்தளம் நிதியுதவி , ஒருங்கிணைந்த ஒர்கனிஸ்மால் அமைப்புகள் ,

First ever 'pioneer' factor found in plants enables cells to change their fate

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IMAGE: Using an experimental technique whereby flowers can be coaxed to form from plant roots, biologists led by the University of Pennsylvania s Doris Wagner uncovered a protein that enables for the.
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Credit: University of Pennsylvania
Cells don t express all the genes they contain all the time. The portion of our genome that encodes eye color, for example, doesn t need to be turned on in liver cells. In plants, genes encoding the structure of a flower can be turned off in cells that will form a leaf.
These unneeded genes are kept from becoming active by being stowed in dense chromatin, a tightly packed bundle of genetic material laced with proteins. ....

Doris Wagner , Meilin Fernandez Garcia , Kenneth Zaret , Roberti Williams , Adam Konkol , Samantha Klasfeld , Yang Zhu , Jun Xiao , Nature Communications , School Of Arts Sciences , Upenn Perlman School Of Medicine , University Of Pennsylvania , University Of Pennsylvania School Arts Sciences , Perelman School Of Medicine , Penn School Of Arts Sciences , Perelman School , Term Professor , Pennsylvania School , Run Jin , Soon Ki Han , Perlman School , National Science Foundation Division , Integrated Organismal Systems , டோரிஸ் வாக்னர் , ரொபேர்த்ி வில்லியம்ஸ் , யாங் ஜு ,

EDGE Program Webinar | NSF - National Science Foundation

January 15, 2021 3:00 PM
Virtual
On January 15 at 2:00 PM EST, the Division of Integrative Organismal Systems (IOS), together with the Divisions of Biological Infrastructure (DBI), Environmental Biology (DEB), and Molecular and Cellular Biosciences (MCB) in the Directorate for Biological Sciences (BIO) at the National Science Foundation (NSF and the National Human Genome Research Institute (NHGRI) of the National Institutes of Health (NIH) will host a webinar about the Enabling Discovery through GEnomics (EDGE) program (NSF 21-546). Following a brief presentation, program directors from all of the Divisions and agencies will be available to answer questions from participants.
Through the EDGE program, the NSF and the NIH support genomic research that addresses the mechanistic basis of complex traits in diverse organisms within the context (environmental, developmental, social, and/or genomic) in which they function. The program also continues to su ....

Edda Floh Thiels , Division Of Integrative Organismal Systems , National Institutes Of Health , National Human Genome Research Institute , Directorate For Biological Sciences , National Science Foundation , Edge Program Webinar , Integrative Organismal Systems , Biological Infrastructure , Environmental Biology , Cellular Biosciences , Biological Sciences , National Institutes , Enabling Discovery , National Science Foundation Jobs , Nsf Jobs , Nsf Careers , Military Veteran Jobs , Minorities In Science , Programs For Veterans , Programs For People With Disabilities , Programs For Recent Graduates , Rotator Position , Temporary Program Director , Science Careers , Science Jobs ,

Tomato's wild ancestor is a genomic reservoir for plant breeders

Thousands of years ago, people in South America began domesticating
Solanum pimpinellifolium, a weedy plant with small, intensely flavored fruit. Over time, the plant evolved into
S. lycopersicum the modern cultivated tomato.
Although today s tomatoes are larger and easier to farm compared to their wild ancestor, they also are less resistant to disease and environmental stresses like drought and salty soil.
S. pimpinellifolium and discovered sections of the genome that underlie fruit flavor, size and ripening, stress tolerance and disease resistance. The results were published in
This reference genome will allow researchers and plant breeders to improve traits like fruit quality and stress tolerance in the tomato, said Fei, for example, by helping them discover new genes in the modern tomato as well as by reintroducing genes from ....

United States , Zhangjun Fei , Diane Okamuro , Division Of Integrative Organismal Systems , Nature Communications , Research News , Nsfpublic Affairs , Us National Science , Boyce Thompson Institute , South America , Science Foundation Funded , Integrative Organismal Systems , ஒன்றுபட்டது மாநிலங்களில் , பிரிவு ஆஃப் ஒருங்கிணைந்த ஒர்கனிஸ்மால் அமைப்புகள் , இயற்கை தகவல்தொடர்புகள் , ஆராய்ச்சி செய்தி , எங்களுக்கு தேசிய அறிவியல் , பாய்ஸ் தாம்சன் நிறுவனம் , தெற்கு அமெரிக்கா , அறிவியல் அடித்தளம் நிதியுதவி , ஒருங்கிணைந்த ஒர்கனிஸ்மால் அமைப்புகள் ,