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Lilly to expand donanemab study in a bid for approval in Alzheimer's disease


Lilly to expand donanemab study in a bid for approval in Alzheimer’s disease
Lilly revealed expanded findings from phase 2 TRAILBLAZER-ALZ study this week
Eli Lilly has revealed expanded findings from a phase 2 trial of its potential Alzheimer’s disease treatment donanemab, and announced plans to expand the clinical programme for the drug in a bid for regulatory approval.
In January, top-line data from the TRAILBLAZER-ALZ trial in patients with early symptomatic Alzheimer’s showed that donanemab slowed cognitive decline by 32% on the Integrated Alzheimer’s Disease Rating Scale (iARDS) compared to placebo.
Although newly reported findings for secondary outcomes within this trial ‘showed no substantial difference’, Lilly highlighted exploratory analyses that showed donanemab slowed the accumulation of tau across key brain regions in Alzheimer’s patients. ....

Daniel Skovronsky , Eli Lilly , Lilly Research Laboratories , Integrated Alzheimer , Disease Rating Scale , Clinical Dementia Rating Scale Sum , Lilly Research , எலி லில்லி , லில்லி ஆராய்ச்சி ஆய்வகங்கள் , ஒருங்கிணைந்த முதுமறதி , நோய் ரேடிஂக் அளவு , மருத்துவ முதுமை ரேடிஂக் அளவு தொகை , லில்லி ஆராய்ச்சி ,