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Novel Anti-Amyloid Slows Cognitive Decline in Phase II Alzheimer Trial

Novel Anti-Amyloid Slows Cognitive Decline in Phase II Alzheimer Trial
medpagetoday.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medpagetoday.com Daily Mail and Mail on Sunday newspapers.

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Experimental Alzheimer's drug could slow cognitive decline in patients, early results suggest

Experimental Alzheimer's drug could slow cognitive decline in patients, early results suggest
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Lilly's donanemab slowed Alzheimer's disease progression in Phase 2 trial: full data presented at AD/PD™ 2021 and published in NEJM

Lilly's donanemab slowed Alzheimer's disease progression in Phase 2 trial: full data presented at AD/PD™ 2021 and published in NEJM
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Lilly Reports Strong Fourth-Quarter and Full-Year 2020 Financial Results

Press release content from PR Newswire. The AP news staff was not involved in its creation.
Lilly Reports Strong Fourth-Quarter and Full-Year 2020 Financial Results
January 29, 2021 GMT
Eli Lilly and Company logo. (PRNewsfoto/Eli Lilly and Company)
INDIANAPOLIS, Jan. 29, 2021 /PRNewswire/ Eli Lilly and Company (NYSE: LLY) today announced financial results for the fourth quarter and full year of 2020.
$ in millions, except
31%
Certain financial information for 2020 and 2019 is presented on both a reported and a non-GAAP basis. Some numbers in this press release may not add due to rounding. Reported results were prepared in accordance with U.S. generally accepted accounting principles (GAAP), include all revenue and expenses recognized during the periods, and reflect Elanco Animal Health (Elanco) as discontinued operations during the first quarter of 2019. Non-GAAP measures reflect adjustments for the items described in the reconciliation tables later ....

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Lilly's Donanemab Slows Clinical Decline of Alzheimer's Disease in Positive Phase 2 Trial

Lilly’s Donanemab Slows Clinical Decline of Alzheimer’s Disease in Positive Phase 2 Trial
Lilly’s Donanemab Slows Clinical Decline of Alzheimer’s Disease
in Positive Phase 2 Trial

BASINGSTOKE, January 12, 2021 – Donanemab, an investigational antibody that targets a modified form of beta amyloid called N3pG, showed significant slowing of decline in a composite measure of cognition and daily function in patients with early symptomatic Alzheimer’s disease compared to placebo in results from Eli Lilly and Company’s Phase 2 TRAILBLAZER-ALZ study. Donanemab met the primary endpoint of change from baseline to 76 weeks in the Integrated Alzheimer s Disease Rating Scale (iADRS), slowing decline by 32 percent relative to placebo, which was statistically significant. The iADRS is a clinical composite tool combining the cognitive measure ADAS-Cog13 and functional measure ADCS-iADL, two commonly used measures in Alzheimer’s disease. ....

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