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Japan biotech startup pushes for mRNA shot suited for mass production

The key benefit of self-replicating vaccines is their efficiency, as they require only a fraction of the dosage of conventional vaccines to trigger a strong immune response. ....

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Low profile thoracic aortic endograft device reduces complications and expands patient pool

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Boston, MA (May 1, 2021) - Preliminary results of a clinical trial, presented today at the AATS 101st Annual Meeting, showed that a new, low-profile thoracic aortic endograft is safe and effective in the treatment of descending thoracic aortic aneurysm or penetrating atherosclerotic ulcer (PAU) diseases. A multi-disciplinary team, led by both cardiac and vascular surgeons as co-investigators, conducted the study in 36 centers in the United States and Japan, enrolling patients between 2016 and 2019.
The trial aimed to measure safety and efficacy of the RELAY®Pro endovascular device, a second-generation product featuring a dramatically reduced profile and a non-bare stent (NBS) configuration. ....

United States , Arizona Heart Institute , University Of Pennsylvania , Christopher Smolock , Wilson Szeto , Joel Corvera , Sina Moainie , Venkatesh Ramaiah , Mel Sharafuddin , Hitoshi Matsuda , Prashanth Vallabhajosyula , Thomas Naslund , Wilsony Szeto , Shinji Miyamoto , Indiana University , Yale University , St Vincent Heart Center , University Of Iowa , Oita University Hospital , National Cerebral , Hospital Of The University Pennsylvania , Penn Presbyterian Medical Center , Vanderbilt University , Cardiovascular Center , Annual Meeting , Penn Presbyterian Medical ,

Japan is late bloomer in race to develop COVID vaccine

Japan is late bloomer in race to develop COVID vaccine
Researchers say Japan’s slow development of a vaccine against COVID-19 is linked to decades of stagnant public funding for universities resulting from government slashing overall higher education and research budgets to cope with dwindling national revenue.
But the pandemic reversed the situation last year when government grants were expanded to support new projects that are collaborations between universities and drug companies.
“Japan is a late bloomer in the fight to develop a domestic vaccine. But with new public grants extended to researchers, there are breakthroughs for a domestic product that will improve the safety and efficiency of currently available vaccines,” explained Dr Naoto Uemura, head of clinical pharmacology at Oita University Hospital. ....

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