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Skeleton of malaria parasite reveals its secrets


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Skeleton of malaria parasite reveals its secrets
Research teams from UNIGE have discovered that the cytoskeleton of the malaria parasite comprises a vestigial form of an organelle called conoid, initially thought to be absent from this species and which could play a role in host invasion.
Plasmodium at the ookinete stage viewed by expansion microscopy. The image shows the cytoskeleton of the pathogen following the labelling of tubulin. The conoid is the ring visible at the upper tip of the cell. © UNIGE/HAMEL
Plasmodium is the parasite causing malaria, one of the deadliest parasitic diseases. The parasite requires two hosts -the Anopheles mosquito and the human- to complete its life cycle and goes through different forms at each stage of its life cycle. Transitioning from one form to the next involves a massive reorganisation of the cytoskeleton. Two teams from the University of Geneva (UNIGE) have shed new light on the cytoskeleton organisation in Plasm ....

Virginie Hamel , Department Of Microbiology , University Of Geneva , Cell Biology , Vestigial Form , Mathieu Brochet , Molecular Medicine , கன்னி ஹ்யாமல் , துறை ஆஃப் நுண்ணுயிரியல் , பல்கலைக்கழகம் ஆஃப் ஜிநீவ , செல் உயிரியல் , ம்யாத்யு சிற்றேடு , மூலக்கூறு மருந்து ,