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High expression of cell death genes may increase risk of early death from lung cancer


High expression of cell death genes may increase risk of early death from lung cancer
Patients with a high number of genes most associated with pathways that lead to cell death in lung cancer are at increased risk of dying early from their disease, researchers report.
Also seemingly paradoxically, patients with high expression of this 21-gene cell death signature the researchers have identified, have indicators that their immune system is attacking the cancer, like higher levels of cytotoxic T cells, which typically kill cancer.
But they also have high levels of molecules that can suppress those T cells, helping transform them into dysfunctional, exhausted T cells, they report in the journal ....

United States , Ravindra Kolhe , Emily Henderson , Centers For Disease , National Cancer Institute , National Human Genome Research Institute , Drug Administration , Cancer Research Institute , College Of Georgia Department Pathology , Georgia Esoteric , Medical College , Georgia Department , Cancer Genome Atlas , National Human Genome Research , Disease Control , Cancer Research , Cell Death , Lung Cancer , Immune System , Pd L1 , ஒன்றுபட்டது மாநிலங்களில் , ரவின்ற கொள்ே , எமிலி ஹென்டர்சன் , மையங்கள் க்கு நோய் , தேசிய புற்றுநோய் நிறுவனம் , தேசிய மனிதன் மரபணு ஆராய்ச்சி நிறுவனம் ,