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Little Benefit Seen for Statin Drug in Knee OA

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The use of atorvastatin (Lipitor) did not reduce cartilage volume loss in patients with knee osteoarthritis (OA) over a period of 2 years, a placebo-controlled study found.
Among patients randomized to receive atorvastatin, 40 mg per day, the reduction of tibial cartilage volume was 1.66% per year, while for those given placebo, the reduction was 2.17%, for a between-group difference of 0.50% (95% CI -0.17 to 1.17,
P=0.14), reported Flavia M. Cicuttini, PhD, of Monash University in Melbourne, Australia, and colleagues.
These findings do not support the use of atorvastatin as a disease-modifying agent in established knee OA, the researchers concluded in their study online in ....

South Australia , Flaviam Cicuttini , Monash University , Western Ontario , Mcmaster Universities Osteoarthritis Index , தெற்கு ஆஸ்திரேலியா , மோனாஷ் பல்கலைக்கழகம் , மேற்கு ஆஂடேரியொ , மக்மாஸ்டர் பல்கலைக்கழகங்கள் ஆஸ்டியோவார்த்ரைடிஸ் குறியீட்டு ,

FDA needs better data to treat women and chronic pain

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Recent hopes of a new treatment for a common chronic pain condition, osteoarthritis (OA), were dashed when a much-anticipated novel OA pain drug was not approved by the FDA’s expert panel because of safety concerns. Currently, there is no targeted therapy for this condition and most patients manage it by using either NSAIDS or opioids and joint replacement surgery when worsening of the joint occurs.
OA, a degenerative chronic pain condition, disproportionately affects women and its symptoms are more severe in women. Research over the years has well documented these sex and gender differences with regard to prevalence, incidence and severity of this disease in knee and hips. This includes women being more likely to undergo knee or hip arthroplasty compared to men. ....

Health Care , Drug Prescriptions , Clinical Trials , ஆரோக்கியம் பராமரிப்பு , மருந்து ப்ரிஸ்க்ரிப்ஶந்ஸ் , மருத்துவ சோதனைகள் ,

Adalimumab: Sold Under the Brand Name Humira - Global Biosimilar Insight Report 2021

Press release content from Business Wire. The AP news staff was not involved in its creation.
Adalimumab: Sold Under the Brand Name Humira - Global Biosimilar Insight Report 2021 - ResearchAndMarkets.com
April 2, 2021 GMT
The “Adalimumab - Biosimilar Insight, 2021” report has been added to ResearchAndMarkets.com’s offering.
This “Adalimumab - Biosimilar Insight, 2021,” report provides comprehensive insights about 34+ companies and 35+ marketed and pipeline drugs in Adalimumab Biosimilars landscape.
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It covers the marketed and pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. ....

United States , Innovent Biologics , Biocon Mylan , Zydus Cadila , Daiichi Sankyo , Tanvex Biopharma , Samsung Bioepis , Fresenius Kabi , Idacio Kromeya , Genor Biopharma , Adalimumab Biosimilars , Coherus Biosciences , Seika Pharma , Abrilada Amsparity , Laura Wood , Synermore Biologics , Office Hours Call , Boehringer Ingelheim , Momenta Pharmaceuticals , E St Office Hours Call , China National Medical Products Administration , Bio Thera Solutions , Hetero Group , National Medical Products Administration , Merck Kgaa Group , Harvest Moon Pharmaceuticals ,

Holmes awarded HHMI fellowship for promising early-career scientists

Holmes
Virologist Autumn Holmes, PhD, a postdoctoral researcher at Washington University School of Medicine in St. Louis, has been named a Hanna H. Gray Fellow by the Howard Hughes Medical Institute (HHMI). The fellowship provides up to $1.4 million over eight years to outstanding early-career scientists. Its aim is to help those with the potential to solve major challenges in the life sciences make the transition to becoming principal investigators.
Holmes’ research focuses on finding new therapies for emerging infectious diseases such as chikungunya. Transmitted by mosquito bite, chikungunya virus causes debilitating, often chronic arthritis in people. While chikungunya is still mostly confined to tropical parts of the planet, the mosquito species that carry the virus are likely to expand their range over the next few decades due to climate change. ....

Hannah Gray , Washington University School Of Medicine , Howard Hughes Medical Institute , Autumn Holmes , Washington University School , Washington University , Infectious Diseases , Climate Change , ஹன்னா சாம்பல் , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி ஆஃப் மருந்து , ஹோவர்ட் ஹக்ஸ் மருத்துவ நிறுவனம் , இலையுதிர் காலம் ஹோம்ஸ் , வாஷிங்டன் பல்கலைக்கழகம் பள்ளி , வாஷிங்டன் பல்கலைக்கழகம் , தொற்று நோய்கள் , காலநிலை மாற்றம் ,

Could a flavonoid found in common fruit and vegetables combat COVID-19?

Researchers in India have gathered and presented a large body of evidence highlight quercetin – a flavonoid molecule found in many common fruits and vegetables – may be developed into drug therapies used to combat COVID-19. ....

Michael Burgess , Michael Burgessapr , Deepu Matthew , Molecular Biology Department , Centre For Plant Biotechnology , Kerala Agricultural University , Beni Suef University Journal , Applied Sciences , Monkey Business Images , Plant Biotechnology , Molecular Biology , Antiviral Drug , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Rheumatoid Arthritis , Spike Protein , மைக்கேல் பர்கஸ் , தீபு மேத்யூ , மூலக்கூறு உயிரியல் துறை , மையம் க்கு ஆலை உயிரி தொழில்நுட்பவியல் , பயன்படுத்தப்பட்டது அறிவியல் , குரங்கு வணிக படங்கள் , ஆலை உயிரி தொழில்நுட்பவியல் , மூலக்கூறு உயிரியல் , கொரோனா வைரஸ் ,