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Synthetic biology circuits can respond within seconds

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Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input.

However, there is often a long lag time between an event such as detecting a molecule and the resulting output, because of the time required for cells to transcribe and translate the necessary genes. MIT synthetic biologists have now developed an alternative approach to designing such circuits, which relies exclusively on fast, reversible protein-protein interactions. This means that there’s no waiting for genes to be transcribed or translated into proteins, so circuits can be turned on much faster within seconds. ....

Bonnie Berger , Brian Teague , Ron Weiss , Tristan Bepler , Deepak Mishra , National Science Foundation Graduate Research Fellowship Program , Artificial Intelligence Laboratory , Department Of Biological Engineering , Institute For Collaborative Biotechnologies , National Institutes Of Health , National Science Foundation , Department Of Biochemistry , University Of Wisconsin , Us Army Research Office , Energy Research Fellowship , Biological Engineering , Simons Professor , Jim Broach , Molecular Biology , Penn State Hershey Medical , Siebel Scholars Award , Research Fellowship , Collaborative Biotechnologies , Research Office , Integrated Synthetic Biology , National Institutes ,

Synthetic biology circuits can respond within seconds

Synthetic biology circuits can respond within seconds
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Bonnie Berger , Brian Teague , Ron Weiss , Tristan Bepler , Deepak Mishra , National Science Foundation Graduate Research Fellowship Program , Artificial Intelligence Laboratory , Department Of Biological Engineering , Institute For Collaborative Biotechnologies , National Institutes Of Health , National Science Foundation , Department Of Biochemistry , University Of Wisconsin , Us Army Research Office , Energy Research Fellowship , Biological Engineering , Simons Professor , Jim Broach , Molecular Biology , Penn State Hershey Medical , Siebel Scholars Award , Research Fellowship , Collaborative Biotechnologies , Research Office , Integrated Synthetic Biology , National Institutes ,

Synthetic biology circuits can respond within seconds

Synthetic biology circuits can respond within seconds
mit.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from mit.edu Daily Mail and Mail on Sunday newspapers.

Bonnie Berger , Brian Teague , Ron Weiss , Tristan Bepler , Deepak Mishra , National Science Foundation Graduate Research Fellowship Program , Artificial Intelligence Laboratory , Department Of Biological Engineering , Institute For Collaborative Biotechnologies , National Institutes Of Health , National Science Foundation , Department Of Biochemistry , University Of Wisconsin , Us Army Research Office , Energy Research Fellowship , Biological Engineering , Simons Professor , Jim Broach , Molecular Biology , Penn State Hershey Medical , Siebel Scholars Award , Research Fellowship , Collaborative Biotechnologies , Research Office , Integrated Synthetic Biology , National Institutes ,

From biofuels and other commodity chemicals to methane production, genomic study peers into mysteries of a goat's gut

From biofuels and other commodity chemicals to methane production, genomic study peers into the mysteries of a goat's gut By Sonia Fernandez Santa. ....

Elmo Wilken , Michelle Omalley , Michaelk Theodorou , Igorv Grigoriev , Asaf Salamov , Xuefeng Nick Peng , Davidl Valentine , Seanp Gilmore , Santa Barbara , Jenniferl Brown , Thomass Lankiewicz , Kerrie Barry , Johk Henske , Department Of Energy , Bioenergy Institute , Harper Adams University , Community Science Program , Institute For Collaborative Biotechnologies , Lawrence Berkeley National Laboratory , National Science Foundation , Department Of Energy Joint Genome Institute , California Nanosystems Institute , President Obama , Nature Microbiology , San Clemente Island Goat , Santa Barbara Zoo ,

Wonder fungi

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Michelle O Malley(link is external) has long been inspired by gut microbes. Since she began studying the herbivore digestive tract, the UC Santa Barbara chemical engineering professor has guided several students to their doctoral degrees, won early and mid-career awards (including a recognition from President Obama), attained tenure and advanced to the position of full professor. She even had three children along the way. A constant through it all: goat poop.
This has been the longest single effort in my lab, said O Malley, who with her research team way back in 2015 first embarked on an ambitious project to characterize gut microbes in large herbivores. The purpose? To understand how these animals manage, via their microbiomes, to extract energy from plant material, particularly the fibrous, non-food parts, where sugars are locked behind tough plant cell walls. Understanding this process could reveal methods for extracting the raw materials necessary for a wide ....

Elmo Wilken , Michelle Omalley , Michaelk Theodorou , Igorv Grigoriev , Asaf Salamov , Xuefeng Nick Peng , Davidl Valentine , Seanp Gilmore , Santa Barbara , Jenniferl Brown , Thomass Lankiewicz , Kerrie Barry , Johk Henske , Department Of Energy , Bioenergy Institute , Harper Adams University , Community Science Program , Institute For Collaborative Biotechnologies , Lawrence Berkeley National Laboratory , National Science Foundation , Department Of Energy Joint Genome Institute , California Nanosystems Institute , Michelleo Malley , President Obama , Nature Microbiology , San Clemente Island Goat ,