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Scientists Identify Genetic Pathway that Suppresses Lou Gehrig's Disease

Date Time
Scientists Identify Genetic Pathway that Suppresses Lou Gehrig’s Disease
Professor Chunghun Lim and his research team in the Department of Biological Sciences unveiled a neuroprotective pathway that suppresses Lou Gehrig’s Disease (ALS).
Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases, such as C9ORF72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). In this study, the research team has identified a neuroprotective pathway of like-Sm protein 12 (LSM12) and exchange protein directly activated by cyclic AMP 1 (EPAC1) that sustains the nucleocytoplasmic RAN gradient and thereby suppresses NCT dysfunction by the C9ORF72-derived poly (glycine-arginine) protein. ....

South Korea , Lou Gehrig , Jongbo Lee , Department Of Biological Sciences , National Research Foundation Of Korea , Korea Health Technology , Suh Kyungbae Foundation , Korean Ministry Of Health , Professor Chunghun Lim , Biological Sciences , National Research Foundation , Korea Health Technology Rd Project , Korean Ministry , Ju Min Park , Ji Hyung Kim , Ministry Of Health , Amyotrophic Lateral Sclerosis , Health Technology , Cell Nucleus , தெற்கு கொரியா , லூ கேஹ்ரிக் , துறை ஆஃப் உயிரியல் அறிவியல் , தேசிய ஆராய்ச்சி அடித்தளம் ஆஃப் கொரியா , கொரியா ஆரோக்கியம் தொழில்நுட்பம் , கொரியன் அமைச்சகம் ஆஃப் ஆரோக்கியம் , உயிரியல் அறிவியல் ,

Network study of responses to unusualness and psychological stress during the COVID-19 outbreak in Korea

Network study of responses to unusualness and psychological stress during the COVID-19 outbreak in Korea
Seunghyong Ryu,
Affiliation
Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea
Affiliation
Gwangju Mental Health and Welfare Commission, Gwangju, Korea
⨯
Mina Kim,
Affiliation
Gwangju Mental Health and Welfare Commission, Gwangju, Korea
⨯
Yu-Ri Lee,
Roles
Data curation,
Investigation
Affiliations
Gwangju Mental Health and Welfare Commission, Gwangju, Korea,
Department of Social Welfare, Nambu University, Gwangju, Korea
⨯
Jonghun Lee,
Roles
Conceptualization,
Formal analysis,
Investigation
Affiliations
Daegu Metropolitan Mental Health and Welfare Center, Daegu, Korea,
Department of Psychiatry, Catholic University of Daegu, College of Medicine, Daegu, Korea ....

South Korea , United States , Republic Of Korea , Akihiro Nishi , Fielding School Of Public Health , Korea Health Industry Development Institute , World Health Organization , Ministry Of Health Welfare , Korea Health Technology , Perceived Stress Scale , Parki H , Leey R , Public Health , Creative Commons Attribution License , Supporting Information , Korea Health Technology Rd Project , Daegu City , East Asian , Covid 19 , Psychological Stress , Network Analysis , Psychological And Psychosocial Issues , தெற்கு கொரியா , ஒன்றுபட்டது மாநிலங்களில் , குடியரசு ஆஃப் கொரியா , பீல்டிங் பள்ளி ஆஃப் பொது ஆரோக்கியம் ,